Genetically engineered microbial remediation of soils co-contaminated by heavy metals and polycyclic aromatic hydrocarbons: advances and ecological risk …

C Wu, F Li, S Yi, F Ge - Journal of Environmental Management, 2021 - Elsevier
Soils contaminated with heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs)
have been becoming a worldwide concerned environmental problem because of …

Engineering wired life: synthetic biology for electroactive bacteria

LJ Bird, BB Kundu, T Tschirhart, AD Corts… - ACS Synthetic …, 2021 - ACS Publications
Electroactive bacteria produce or consume electrical current by moving electrons to and
from extracellular acceptors and donors. This specialized process, known as extracellular …

Improved bacterial recombineering by parallelized protein discovery

TM Wannier, A Nyerges… - Proceedings of the …, 2020 - National Acad Sciences
Exploiting bacteriophage-derived homologous recombination processes has enabled
precise, multiplex editing of microbial genomes and the construction of billions of …

New insights on steroid biotechnology

L Fernández-Cabezón, B Galán, JL García - Frontiers in Microbiology, 2018 - frontiersin.org
Nowadays steroid manufacturing occupies a prominent place in the pharmaceutical industry
with an annual global market over $10 billion. The synthesis of steroidal active …

Recombineering and MAGE

TM Wannier, PN Ciaccia, AD Ellington… - Nature Reviews …, 2021 - nature.com
Recombination-mediated genetic engineering, also known as recombineering, is the
genomic incorporation of homologous single-stranded or double-stranded DNA into …

Recent biotechnological trends in lactic acid bacterial fermentation for food processing industries

T Raj, K Chandrasekhar, AN Kumar, SH Kim - Systems Microbiology and …, 2022 - Springer
Lactic acid bacteria (LAB) are non-mobile, gram-positive, non-spore-forming, micro-
aerophilic microorganisms widely explored as starter cultures food industry to enhance the …

Engineering microbial hosts for production of bacterial natural products

MM Zhang, Y Wang, EL Ang, H Zhao - Natural product reports, 2016 - pubs.rsc.org
Covering up to end 2015 Microbial fermentation provides an attractive alternative to
chemical synthesis for the production of structurally complex natural products. In most cases …

[HTML][HTML] A CRISPR-Cas9 assisted non-homologous end-joining strategy for one-step engineering of bacterial genome

T Su, F Liu, P Gu, H Jin, Y Chang, Q Wang, Q Liang… - Scientific reports, 2016 - nature.com
Homologous recombination-mediated genome engineering has been broadly applied in
prokaryotes with high efficiency and accuracy. However, this method is limited in realizing …

Genome editing of lactic acid bacteria: opportunities for food, feed, pharma and biotech

RA Börner, V Kandasamy, AM Axelsen… - FEMS microbiology …, 2019 - academic.oup.com
This mini-review provides a perspective of traditional, emerging and future applications of
lactic acid bacteria (LAB) and how genome editing tools can be used to overcome current …

Next generation prokaryotic engineering: the CRISPR-Cas toolkit

I Mougiakos, EF Bosma, WM de Vos… - Trends in …, 2016 - cell.com
The increasing demand for environmentally friendly production processes of green
chemicals and fuels has stimulated research in microbial metabolic engineering. CRISPR …