Deciphering the chameleonic chemistry of allenols: breaking the taboo of a onetime esoteric functionality

JM Alonso, P Almendros - Chemical Reviews, 2021 - ACS Publications
The allene functionality has participated in one of the most exciting voyages in organic
chemistry, from chemical curiosities to a recurring building block in modern organic …

Synthesis and transformations of nitrones for organic synthesis

SI Murahashi, Y Imada - Chemical reviews, 2019 - ACS Publications
Nitrones are important compounds and are highly useful in many aspects. The first part
describes the methods for synthesis of nitrones, which are useful and environmentally …

Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis

J Robertson, K Stevens - Natural Product Reports, 2017 - pubs.rsc.org
Covering: 2013 up to the end of 2015 This review covers the isolation and structure of new
pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of …

Alkoxyallenes as building blocks for organic synthesis

R Zimmer, HU Reissig - Chemical Society Reviews, 2014 - pubs.rsc.org
Alkoxyallenes are unusually versatile C3 building blocks in organic synthesis. Hence this
tutorial review summarizes the most important transformations, including subsequent …

Pyrrolizidine alkaloids

J Tamariz, E Burgueño-Tapia, MA Vázquez… - The alkaloids: chemistry …, 2018 - Elsevier
Naturally occurring pyrrolizidine alkaloids (PAs) are isolated from plants and other sources.
The interest of the scientific community in these compounds owes itself to their high toxicity …

Direct synthesis of imino-C-nucleoside analogues and other biologically active iminosugars

M Bergeron-Brlek, M Meanwell, R Britton - Nature communications, 2015 - nature.com
Iminosugars have attracted increasing attention as chemical probes, chaperones and leads
for drug discovery. Despite several clinical successes, their de novo synthesis remains a …

New frontiers on human safe insecticides and fungicides: An opinion on trehalase inhibitors

C Matassini, C Parmeggiani, F Cardona - Molecules, 2020 - mdpi.com
In the era of green economy, trehalase inhibitors represent a valuable chance to develop
non-toxic pesticides, being hydrophilic compounds that do not persist in the environment …

Human Acid β‐Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease

C Parmeggiani, S Catarzi, C Matassini… - …, 2015 - Wiley Online Library
A collection of carbohydrate‐derived iminosugars belonging to three structurally diversified
sub‐classes (polyhydroxylated pyrrolidines, piperidines, and pyrrolizidines) was evaluated …

Synthesis and glycosidase inhibition of australine and its fluorinated derivatives

YX Li, Y Shimada, K Sato, A Kato, W Zhang… - Organic …, 2015 - ACS Publications
Australine (1), 7-epi-australine (2), and their C-7-fluorinated derivatives 4 and 5 have been
synthesized efficiently from d-arabinose-derived cyclic nitrone 11. Fluorination at the C-7 …

Stereodivergent routes in organic synthesis: carbohydrates, amino acids, alkaloids and terpenes

C Nájera, F Foubelo, JM Sansano… - Organic & Biomolecular …, 2020 - pubs.rsc.org
The natural occurrence of enantiomers and diastereomers is often encountered. In addition,
the synthesis of these stereoisomers is important for structure determination and for the …