Emerging biomarkers and molecular targets for precision medicine in cervical cancer

P Garg, M Krishna, AR Subbalakshmi… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Cervical cancer remains a significant global health burden, necessitating innovative
approaches for improved diagnostics and personalized treatment strategies. Precision …

Single-cell transcriptomics reveals cellular heterogeneity and molecular stratification of cervical cancer

C Li, H Wu, L Guo, D Liu, S Yang, S Li… - Communications biology, 2022 - nature.com
Cervical cancer (CC) is the most common gynecological malignancy, whose cellular
heterogeneity has not been fully understood. Here, we performed single-cell RNA …

Chlamydia trachomatis infection co-operatively enhances HPV E6-E7 oncogenes mediated tumorigenesis and immunosuppression

N Challagundla, J Chrisophe-Bourdon… - Microbial …, 2023 - Elsevier
Chlamydia trachomatis and human papilloma virus (HPV) are the two most common
sexually transmitted infections among women. HPV infection can increase the risk of cervical …

Tumor lineage-specific immune response in brain metastatic disease: opportunities for targeted immunotherapy regimen?

S Najjary, JM Kros, W de Koning, D Vadgama… - Acta neuropathologica …, 2023 - Springer
Metastases in the brain are the most severe and devastating complication of cancer. The
incidence of brain metastasis is increasing. Therefore, the need of finding specific druggable …

STING agonist inflames the cervical cancer immune microenvironment and overcomes anti-PD-1 therapy resistance

T Li, W Zhang, M Niu, Y Wu, X Deng… - Frontiers in Immunology, 2024 - frontiersin.org
Background Cervical cancer poses a significant global threat to women's health. However,
current therapeutic interventions, such as radiotherapy, chemotherapy, surgical resection …

Ras-Targeting Stabilized Peptide Increases Radiation Sensitivity of Cancer Cells

W Qin, X Wei, D Yang, Q Luo, M Huang… - Bioconjugate …, 2024 - ACS Publications
Radiation therapy is one of the most common treatments for cancer. However, enhancing
tumors' radiation sensitivity and overcoming tolerance remain a challenge. Previous studies …

Unraveling Differences in Molecular Mechanisms and Immunological Contrasts between Squamous Cell Carcinoma and Adenocarcinoma of the Cervix

M Salarzaei, RLO van de Laar… - International Journal of …, 2024 - mdpi.com
This study aims to refine our understanding of the inherent heterogeneity in cervical cancer
by exploring differential gene expression profiles, immune cell infiltration dynamics, and …

Contrast-enhanced ultrasound combined with elastic imaging for predicting the efficacy of concurrent chemoradiotherapy in cervical cancer: a feasibility study

X ZHAO, Y Ma, X CEHN - Frontiers in Oncology, 2024 - frontiersin.org
Results: There was no notable difference in overall clinical data between the CR group and
the PR group (P> 0.05). Before treatment, there were no statistically significant differences in …

LncRNA HAND2-AS1 在宫颈癌患者血清中的表达及临床意义.

张晓科, 褚艳荣, 崔发财 - Journal of Modern Medicine & …, 2024 - search.ebscohost.com
目的探究长链非编码RNA (LncRNA) 心脏和神经嵴衍生物表达转录本2 反义序列1 (HAND2-
AS1) 在宫颈癌患者血清中的表达及其临床意义. 方法选取2019 年1 月至2020 年6 …

[PDF][PDF] Multiple Omics Profiling of the PDAC Tumor Immune Microenvironment

W de Koninig, W de Koning - core.ac.uk
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach,
begin to multiply out of control and form a mass. Pancreatic cancer is an aggressive cancer …