Let's talk about sex: Differences in drug therapy in males and females
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …
man?'Perhaps unintended, such narration extends to the reality of current drug …
Sex as a biological variable: a 5-year progress report and call to action
ME Arnegard, LA Whitten, C Hunter… - Journal of Women's …, 2020 - liebertpub.com
A little over 5 years ago, the US National Institutes of Health (NIH) announced the intention
to develop policies to require applicants to report plans to balance male and female cells …
to develop policies to require applicants to report plans to balance male and female cells …
Sex differences and sex bias in human circadian and sleep physiology research
Growing evidence shows that sex differences impact many facets of human biology. Here
we review and discuss the impact of sex on human circadian and sleep physiology, and we …
we review and discuss the impact of sex on human circadian and sleep physiology, and we …
A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research
Natural products continue to be an important source of medicines and drug templates.
Indeed, it has been estimated that approximately a third of all Food and Drug Administration …
Indeed, it has been estimated that approximately a third of all Food and Drug Administration …
Jumonji domain‐containing protein‐3 (JMJD3) promotes myeloid fibroblast activation and macrophage polarization in kidney fibrosis
Background and Purpose Renal fibrosis is a common feature of chronic kidney disease.
Myeloid fibroblasts and macrophages contribute significantly to the pathogenesis of renal …
Myeloid fibroblasts and macrophages contribute significantly to the pathogenesis of renal …
Sex and adverse events of adjuvant chemotherapy in colon cancer: an analysis of 34 640 patients in the ACCENT database
Background Adjuvant chemotherapy is a standard treatment option for patients with stage III
and high-risk stage II colon cancer. Sex is one of several factors responsible for the wide …
and high-risk stage II colon cancer. Sex is one of several factors responsible for the wide …
The underestimated sex: A review on female animal models of depression
Major depression (MD) is the most common psychiatric disorder, predicted to affect around
264 million people worldwide. Although the etiology of depression remains elusive, the …
264 million people worldwide. Although the etiology of depression remains elusive, the …
The glucose tolerance test in mice: Sex, drugs and protocol
MR Kennard, M Nandi, S Chapple… - Diabetes, Obesity and …, 2022 - Wiley Online Library
Aim To establish the impact of sex, dosing route, fasting duration and acute habituation
stress on glucose tolerance test (GTT) measurements used in the preclinical evaluation of …
stress on glucose tolerance test (GTT) measurements used in the preclinical evaluation of …
Aromatase inhibition and ketamine in rats: sex-differences in antidepressant-like efficacy
S Ledesma-Corvi, J Jornet-Plaza… - Biology of sex …, 2023 - Springer
Background Ketamine has been recently approved to treat resistant depression; however
preclinical studies showed sex differences in its efficacy. Sex steroids, such as estrogens …
preclinical studies showed sex differences in its efficacy. Sex steroids, such as estrogens …
Unmasking the adverse impacts of sex bias on science and research animal welfare
EA Nunamaker, PV Turner - Animals, 2023 - mdpi.com
Simple Summary Sex bias—the use of one sex over the other—is a common practice in
biomedical research, typically with over selection of male animals. There are a number of …
biomedical research, typically with over selection of male animals. There are a number of …