Advancing Synthetic Hydrogels through Nature‐Inspired Materials Chemistry

BG Soliman, AK Nguyen, JJ Gooding… - Advanced …, 2024 - Wiley Online Library
Synthetic extracellular matrix (ECM) mimics that can recapitulate the complex biochemical
and mechanical nature of native tissues are needed for advanced models of development …

Beyond Fmoc: A review of aromatic peptide capping groups

AD Martin, P Thordarson - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Self-assembling short peptides have attracted widespread interest due to their tuneable,
biocompatible nature and have potential applications in energy materials, tissue …

Controlling the assembly and properties of low-molecular-weight hydrogelators

ER Draper, DJ Adams - Langmuir, 2019 - ACS Publications
Low-molecular-weight gels are formed by the self-assembly of small molecules into fibrous
networks that can immobilize a significant amount of solvent. Here, we focus on our work …

Drying affects the fiber network in low molecular weight hydrogels

LLE Mears, ER Draper, AM Castilla, H Su… - …, 2017 - ACS Publications
Low molecular weight gels are formed by the self-assembly of a suitable small molecule
gelator into a three-dimensional network of fibrous structures. The gel properties are …

Using small-angle scattering and contrast matching to understand molecular packing in low molecular weight gels

ER Draper, B Dietrich, K McAulay, C Brasnett… - Matter, 2020 - cell.com
It is difficult to determine exactly the molecular packing in the aggregates in low molecular
weight gels. Attempts to understand the packing have been made using X-ray diffraction, but …

Controlled tuning of the properties in optoelectronic self-sorted gels

ER Cross, S Sproules, R Schweins… - Journal of the …, 2018 - ACS Publications
Multicomponent supramolecular gels have great potential for optoelectronics. Ideally, we
could control the self-assembly of multiple components across many length scales, from the …

Using chirality to influence supramolecular gelation

K McAulay, B Dietrich, H Su, MT Scott, S Rogers… - Chemical …, 2019 - pubs.rsc.org
Most low molecular weight gelators are chiral, with racemic mixtures often unable to form
gels. Here, we show an example where all enantiomers, diastereomers and racemates of a …

Development and Characterization of Nanoscale Gel-Core Liposomes Using a Short Self-Assembled Peptide Hydrogel: Implications for Drug Delivery

G Duché, C Heu, P Thordarson - ACS Applied Nano Materials, 2023 - ACS Publications
Targeted drug delivery systems, delivering drugs to specific locations, are an emerging
research interest spanning the fields of nanotechnology, bionanotechnology, and precision …

Self-assembly of thyminyl l-tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems

PL Scognamiglio, C Riccardi, R Palumbo… - Journal of Nanostructure …, 2024 - Springer
The design, synthesis and characterization of a novel nucleoamino acid derivative based on
an l-tryptophanamide functionalised with a thymine nucleobase (named TrpT) is here …

Differently N‐capped analogues of Fmoc‐FF

C Diaferia, E Rosa, E Gallo, G Morelli… - … –A European Journal, 2023 - Wiley Online Library
Short and ultra‐short peptides have been recently envisioned as excellent building blocks
for the formulation of hydrogels with appealing properties. Due to its simplicity and capability …