Engineering and functionalization of gelatin biomaterials: From cell culture to medical applications

AB Bello, D Kim, D Kim, H Park… - Tissue Engineering Part B …, 2020 - liebertpub.com
Health care and medicine were revolutionized in recent years by the development of
biomaterials, such as stents, implants, personalized drug delivery systems, engineered …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Hydrogel-based fiber biofabrication techniques for skeletal muscle tissue engineering

M Volpi, A Paradiso, M Costantini… - ACS Biomaterials …, 2022 - ACS Publications
The functional capabilities of skeletal muscle are strongly correlated with its well-arranged
microstructure, consisting of parallelly aligned myotubes. In case of extensive muscle loss …

Bioinks and bioprinting strategies for skeletal muscle tissue engineering

M Samandari, J Quint… - Advanced …, 2022 - Wiley Online Library
Skeletal muscles play important roles in critical body functions and their injury or disease
can lead to limitation of mobility and loss of independence. Current treatments result in …

Emulsion-templated microparticles with tunable stiffness and topology: Applications as edible microcarriers for cultured meat

SCP Norris, NS Kawecki, AR Davis, KK Chen… - Biomaterials, 2022 - Elsevier
Cultured meat has potential to diversify methods for protein production, but innovations in
production efficiency will be required to make cultured meat a feasible protein alternative …

Microtubule-based transport is essential to distribute RNA and nascent protein in skeletal muscle

LT Denes, CP Kelley, ET Wang - Nature communications, 2021 - nature.com
While the importance of RNA localization in highly differentiated cells is well appreciated,
basic principles of RNA localization in skeletal muscle remain poorly characterized. Here …

Recent advances in the application of natural and synthetic polymer-based scaffolds in musculoskeletal regeneration

B Ye, B Wu, Y Su, T Sun, X Guo - Polymers, 2022 - mdpi.com
The musculoskeletal system plays a critical role in providing the physical scaffold and
movement to the mammalian body. Musculoskeletal disorders severely affect mobility and …

Gellan fluid gel as a versatile support bath material for fluid extrusion bioprinting

AM Compaan, K Song, Y Huang - ACS applied materials & …, 2019 - ACS Publications
Biomedical applications of three-dimensional (3D) printing demand complex hydrogel-
based constructs laden with living cells. Advanced support materials facilitate the fabrication …

Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation

LT Denes, LA Riley, JR Mijares, JD Arboleda, K McKee… - Skeletal muscle, 2019 - Springer
Background Skeletal muscle contributes to roughly 40% of lean body mass, and its loss
contributes to morbidity and mortality in a variety of pathogenic conditions. Significant …

Programmable scaffolds with aligned porous structures for cell cultured meat

Y Chen, W Zhang, X Ding, S Ding, C Tang, X Zeng… - Food Chemistry, 2024 - Elsevier
Porous scaffolds for cell cultured meat are currently limited in the food-grade material
requirements, the cell adhesion, proliferation, and differentiation capacities, and the ignored …