Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

Recent observations related to the structure of the cytoskeleton in neurons and novel
cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases …

Traumatic brain injury is a risk factor for subsequent neurodegenerative disease, including
chronic traumatic encephalopathy, a tauopathy mostly associated with repetitive concussion …

Alzheimer's disease (AD) is characterised by synaptic dysfunction accompanied by the
microscopically visible accumulation of pathological protein deposits and cellular dystrophy …

Chronic cerebral hypoperfusion (CCH) may lead to the cognitive dysfunction, but the
underlying mechanisms are unclear. EGB761, extracted from Ginkgo biloba and as a …

Brain synapses are neuronal structures of the greatest interest. For a long time, however, the
knowledge about them was variable, and interest was mostly focused on their pre-synaptic …

Endemic arsenism is a worldwide health problem. Chronic arsenic exposure results in
cognitive dysfunction due to arsenic and its metabolites accumulating in hippocampus. As …

Drebrin is a key regulator of actin cytoskeleton in neuronal cells which is critical for synaptic
plasticity, neuritogenesis, and neuronal migration. It is also known to orchestrate a cross-talk …

Dendritic spines are small, thin, hair-like protrusions found on the dendritic processes of
neurons. They serve as independent compartments providing large amplitudes of Ca2+ …

Neural networks with precise connection are compulsory for learning and memory. Various
cellular events occur during the genesis of dendritic spines to their maturation, synapse …