Diabetes mellitus (DM) is a growing health concern in society. Type 1 and type 2 DM are the
two main types of diabetes; both types are chronic diseases that affect glucose metabolism …

Glycogen is a branched polymer of glucose which serves as a reservoir of glucose units.
The two largest deposits in mammals are in the liver and skeletal muscle but many cells are …

Conversion of glucose into glycogen is a major pathway that contributes to the removal of
glucose from the portal vein by the liver in the postprandial state. It is regulated in part by the …

Type 2 diabetes is a complex disorder with diminished insulin secretion and insulin action
contributing to the hyperglycemia and wide range of metabolic defects that underlie the …

Liver glycogen is synthesized after a meal in response to an increase in blood glucose
concentration in the portal vein and endocrine and neuroendocrine signals, and is degraded …

Traditionally, glycogen synthase (GS) has been considered to catalyze the key step of
glycogen synthesis and to exercise most of the control over this metabolic pathway …

The regulation of the hepatic glucose output through glycogenolysis is an important target
for type 2 diabetes therapy. Glycogenolysis is catalyzed in liver, muscle and brain by tissue …

В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Type-2 diabetes is associated with impaired glucose clearance by the liver in the
postprandial state, and with elevated glucose production in the post-absorptive state. New …

Multiple insulin-regulated enzymes participate in hepatic glycogen synthesis, and the rate-
controlling step responsible for insulin stimulation of glycogen synthesis is unknown. We …