Therapeutic targeting of the hypoxic tumour microenvironment

DC Singleton, A Macann, WR Wilson - Nature reviews Clinical oncology, 2021 - nature.com
Hypoxia is prevalent in human tumours and contributes to microenvironments that shape
cancer evolution and adversely affect therapeutic outcomes. Historically, two different …

Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models

P Jain, H Kathuria, N Dubey - Biomaterials, 2022 - Elsevier
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …

Microporous water with high gas solubilities

DP Erdosy, MB Wenny, J Cho, C DelRe, MV Walter… - Nature, 2022 - nature.com
Liquids with permanent microporosity can absorb larger quantities of gas molecules than
conventional solvents, providing new opportunities for liquid-phase gas storage, transport …

The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population

K Jin, JW Simpkins, X Ji, M Leis… - Aging and …, 2014 - pmc.ncbi.nlm.nih.gov
Due to the aging of the global population and the derivative increase in aging-related non-
communicable diseases and their economic burden, there is an urgent need to promote …

Two-photon luminescent metal complexes for bioimaging and cancer phototherapy

Y Chen, R Guan, C Zhang, J Huang, L Ji… - Coordination Chemistry …, 2016 - Elsevier
Possessing important advantages over conventional one-photon excited emission such as
great depth discrimination and reduced photo-damage, two-photon excited emission (TPE) …

E. coli Membrane Vesicles as a Catalase Carrier for Long-Term Tumor Hypoxia Relief to Enhance Radiotherapy

W Zai, L Kang, T Dong, H Wang, L Yin, S Gan, W Lai… - ACS …, 2021 - ACS Publications
Hypoxia is one of the most important factors that limit the effect of radiotherapy, and the
abundant H2O2 in tumor tissues will also aggravate hypoxia-induced radiotherapy …

Advances in nanomaterials for treatment of hypoxic tumor

MZ Zou, WL Liu, HS Chen, XF Bai, F Gao… - National Science …, 2021 - academic.oup.com
The hypoxic tumor microenvironment is characterized by disordered vasculature and rapid
proliferation of tumors, resulting from tumor invasion, progression and metastasis. The …

Rescuing cardiac cells and improving cardiac function by targeted delivery of oxygen-releasing nanoparticles after or even before acute myocardial infarction

Y Guan, H Niu, J Wen, Y Dang, M Zayed, J Guan - ACS nano, 2022 - ACS Publications
Myocardial infarction (MI) causes massive cell death due to restricted blood flow and oxygen
deficiency. Rapid and sustained oxygen delivery following MI rescues cardiac cells and …

3D bioprinting at the frontier of regenerative medicine, pharmaceutical, and food industries

Q Ramadan, M Zourob - Frontiers in Medical Technology, 2021 - frontiersin.org
3D printing technology has emerged as a key driver behind an ongoing paradigm shift in the
production process of various industrial domains. The integration of 3D printing into tissue …

Lipid monolayer collapse and microbubble stability

JJ Kwan, MA Borden - Advances in colloid and interface science, 2012 - Elsevier
Microbubbles are micrometer-size gaseous particles suspended in water, and they are often
stabilized by a lipid monolayer shell. Natural microbubbles are found in freshwater and …