Esophageal cancers, largely adenocarcinoma in Western countries and squamous cell
cancer in Asia, present a significant burden of disease and remain one of the most lethal of …

Angle-resolved low-coherence interferometry (a/LCI) is an optical technique that enables
depth-specific measurements of nuclear morphology, with applications to detecting …

Structural optical coherence tomography (OCT) images of tissue stand to benefit from
greater functionalization and quantitative interpretation. The OCT attenuation coefficient µ …

Optical coherence tomography (OCT) leverages light scattering by biological tissues as
endogenous contrast to form structural images. Light scattering behavior is dictated by the …

We present a prospective clinical study using angle-resolved low-coherence interferometry
(a/LCI) to detect cervical dysplasia via depth resolved nuclear morphology measurements …

Significance Azimuth-resolved optical scattering signals obtained from cell nuclei are
sensitive to changes in their internal refractive index profile. These two-dimensional signals …

Angle-resolved low-coherence interferometry (a/LCI) measures depth-resolved angular
scattering for cell nuclear morphology analysis. 2D a/LCI, developed to collect across two …

We demonstrate the reconstruction of angle-resolved optical backscattering after
transmission through a multimode fiber. Angle-resolved backscattering is an important tool …

We present a machine learning method for detecting and staging cervical dysplastic tissue
using light scattering data based on a convolutional neural network (CNN) architecture …

Cervical cancer is one of the most common gynecologic malignancies with significant
morbidity and mortality globally. However, most pre-cancers are easily treatable such that …