Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …

In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …

Microbial fatty acid-derived fuels have emerged as promising alternatives to petroleum-
based transportation fuels. Here we report a modular engineering approach that …

Recent concerns over the sustainability of petrochemical-based processes for production of
desired chemicals have fueled research into alternative modes of production. Metabolic …

The idea of renewable and regenerative resources has inspired research for more than a
hundred years. Ideally, the only spent energy will replenish itself, like plant material …

While conservation of ATP is often a desirable trait for microbial production of chemicals, we
demonstrate that additional consumption of ATP may be beneficial to drive product formation …

Plants possess myriads of secondary metabolites with a broad spectrum of health-promoting
benefits. To date, plant extraction is still the primary route to produce high-value natural …

Engineering Plant Secondary Metabolism in Microbial Systems | Plant Physiology | Oxford
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Although natural products and synthetic small molecules both serve important medicinal
functions, their structures and chemical properties are relatively distinct. To expand the …

Natural products and their derivatives play an important role in modern healthcare as
frontline treatments for many diseases and as inspiration for chemically synthesized …