Osteoarthritis results in irreparable loss of articular cartilage. Due to its avascular nature and
low mitotic activity, cartilage has little intrinsic capacity for repair. Cartilage loss leads to pain …

In the absence of timely and proper treatments, injuries to articular cartilage (AC) can lead to
cartilage degeneration and ultimately result in osteoarthritis. Regenerative medicine and …

Objective To evaluate effectiveness, in terms of patient-reported outcome measures, of
platelet-rich plasma (PRP) injections for knee osteoarthritis compared to placebo and other …

Background: Platelet-rich plasma (PRP) is gaining large interest in clinical practice as a
minimally invasive injective treatment for knee osteoarthritis (OA). Different preparation …

В статье впервые подробно представлена распространенность остеоартрита (ОА),
рассмотрены предикторы развития и прогрессирования заболевания. Описаны …

Fibroblast activation protein (Fap) is a serine protease that degrades denatured type I
collagen, α2-antiplasmin and FGF21. Fap is highly expressed in bone marrow stromal cells …

Background: Intra-articular microfragmented adipose tissue (MF-AT) injections have been
proposed for the treatment of knee osteoarthritis (OA). Purpose: To compare a single …

Background: Genicular artery embolization (GAE) is an innovative technique that has been
investigated as a supplementary treatment method for chronic pain secondary to knee …

Purpose To compare the number and properties of bone marrow stromal cells (BMSCs)
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …

Objectives To quantify the placebo effect of intraarticular injections for knee osteoarthritis in
terms of pain, function, and objective outcomes. Factors influencing placebo effect were …