Recent calorimetric studies of interactions between small molecules and biomolecular
targets have generated renewed interest in the phenomenon of entropy-enthalpy …

Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

The Stability of Cyclodextrin Complexes in Solution | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted. Most …

Oil and water do not mix. The disaffinity of oil for water, with its unusual temperature
dependence, is called the hydrophobic effect. It is important to understand the factors …

▪ Abstract Heat capacity (Cp) is one of several major thermodynamic quantities commonly
measured in proteins. With more than half a dozen definitions, it is the hardest of these …

Hydrophobic interactions are driven by the combined influence of the direct attraction
between oily solutes and an additional water-mediated interaction whose magnitude (and …

The structure of water in the hydration shells of small hydrophobic solutes was investigated
through molecular dynamics. The results show that a subset of water molecules in the first …

We have used femtosecond midinfrared spectroscopy to study the orientational mobility of
water molecules in the hydration shells of hydrophobic groups. Our results show that …

The enthalpically favoured hydration of hydrophobic entities, termed hydrophobic hydration,
impacts the phase behaviour of numerous amphiphiles in water. Here, we show …

Kosmotropic cosolvents added to an aqueous solution promote the aggregation of
hydrophobic solute particles, while chaotropic cosolvents act to destabilise such aggregates …