D Borsook, AM Youssef, L Simons, I Elman… - Pain, 2018 - journals.lww.com
It is well-recognized that, despite similar pain characteristics, some people with chronic pain recover, whereas others do not. In this review, we discuss possible contributions and …
Pain and stress share significant conceptual and physiological overlaps. Both phenomena challenge the body's homeostasis and necessitate decision-making to help animals adapt to …
Abstract See Tracey (doi: 10.1093/brain/aww147) for a scientific commentary on this article. Mechanisms of chronic pain remain poorly understood. We tracked brain properties in …
J Strahler, N Skoluda, MB Kappert, UM Nater - … & Biobehavioral Reviews, 2017 - Elsevier
Salivary cortisol (sCort) and salivary alpha-amylase (sAA) constitute proxy measures of the two major stress response systems, ie the hypothalamic-pituitary-adrenal axis and the …
W Zhao, L Zhao, X Chang, X Lu… - Proceedings of the …, 2023 - National Acad Sciences
Numerous studies have investigated the impacts of common types of chronic pain (CP) on patients' cognitive function and observed that CP was associated with later dementia. More …
While chronic pain is considered by some to be a CNS disease, little is understood about underlying neurobiological mechanisms. Addiction models have heuristic value in this …
Major depressive disorder (MDD), anxiety disorders (ANX), and chronic pain (CP) are closely-related disorders with both high degrees of comorbidity among them and shared risk …
Stress is present in everyday life in various forms and situations. Two stressors frequently investigated are physiological and psychosocial stress. Besides similar subjective and …
A wealth of research over the past 2 decades has expanded our understanding of the impact of early‐life adversity on physiological function and, consequently, health and wellbeing in …