Data-driven modeling of core gene regulatory network underlying leukemogenesis in IDH mutant AML

A Katebi, X Chen, D Ramirez, S Li, M Lu - npj Systems Biology and …, 2024 - nature.com
Acute myeloid leukemia (AML) is characterized by uncontrolled proliferation of poorly
differentiated myeloid cells, with a heterogenous mutational landscape. Mutations in IDH1 …

The potential role of serum extracellular vesicle derived small RNAs in AML research as non-invasive biomarker

L Li, V Mussack, A Görgens, E Pepeldjiyska… - Nanoscale …, 2023 - pubs.rsc.org
Background: Extracellular vesicles (EV) are cell-derived vesicles released by all cells in
health and disease. Accordingly, EVs are also released by cells in acute myeloid leukemia …

Comprehensive analysis of cuproptosis-associated LncRNAs predictive value and related CeRNA network in acute myeloid leukemia

C Cao, T Wang, Y Luo, Y Zhang, Y Dai, Y Shen - Heliyon, 2023 - cell.com
Background Acute myeloid leukemia (AML) is characterized by a high recurrence and
mortality rate. Cuproptosis is involved in cell death regulation in in a variety of solid tumors …

MiR-185-5p suppresses acute myeloid leukemia by inhibiting GPX1

B Pang, H Mao, J Wang, W Yang - Microvascular research, 2022 - Elsevier
Acute myeloid leukemia (AML) has been characterized by the swift development of
abnormal cells in the bone marrow. This research aimed to examine the impacts of the miR …

Specificity protein 1/3 regulate T-cell acute lymphoblastic leukemia cell proliferation and apoptosis through β-catenin by acting as targets of miR-495-3p

B Zheng, Y Geng, Y Li, H Huang, A Liu - Annals of Hematology, 2024 - Springer
T-cell acute lymphoblastic leukemia (T-ALL) is a hematologic heterogeneous disease. This
study explored the mechanism of specificity protein 1/3 (Sp1/3) in T-ALL cells through β …

[PDF][PDF] A Meta-Analysis of microRNA profiling data in Acute Myeloid Leukemia

ΓΠΚ Μπαράκος - 2023 - ir.lib.uth.gr
Objectives: A meta-analysis to decipher the AML miRNA deregulation compared to healthy
controls and to investigate possible roles of significantly deregulated miRNAs. Methods: A …

A Bioinformatics Analysis of circRNA/miRNA/mRNA Interactions in Acute Myeloid Leukemia

C Erdoğan, M Kaya, I Suer - Experimed, 2023 - dergipark.org.tr
Objective: Acute myeloid leukemia (AML) is a lethal type of cancer associated with
dysregulation of progenitor hematopoietic stem cell behavior and its incidence is …

BCR: ABL1-induced leukemogenesis: impacts of miR-495 and circadian clock

Y Rittavee - 2022 - theses.hal.science
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the
presence of an abnormal chimeric fusion protein BCR:: ABL1. The treatment of CML has …

[PDF][PDF] Preparation of Cu cluster catalysts by simultaneous cooling-microwave heating: application in radical cascade annulation

L Song, R Manno, P Ranjan, V Sebastian… - Nanoscale …, 2021 - lirias.kuleuven.be
One of the hallmarks of microwave irradiation is its selective heating mechanism. In the past
30 years, alternative designs of chemical reactors have been introduced, where the …