Insights into Acinetobacter baumannii: A Review of Microbiological, Virulence, and Resistance Traits in a Threatening Nosocomial Pathogen

C Ayoub Moubareck, D Hammoudi Halat - Antibiotics, 2020 - mdpi.com
Being a multidrug-resistant and an invasive pathogen, Acinetobacter baumannii is one of
the major causes of nosocomial infections in the current healthcare system. It has been …

Treatment of infections caused by multidrug-resistant gram-negative bacteria: Report of the British society for antimicrobial chemotherapy/healthcare infection society …

PM Hawkey, RE Warren, DM Livermore… - Journal of …, 2018 - academic.oup.com
Abstract The Working Party makes more than 100 tabulated recommendations in
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …

Antibiotic treatment of infections due to carbapenem-resistant Enterobacteriaceae: systematic evaluation of the available evidence

ME Falagas, P Lourida, P Poulikakos… - Antimicrobial agents …, 2014 - Am Soc Microbiol
We sought to evaluate the effectiveness of the antibiotic treatment administered for infections
caused by carbapenemase-producing Enterobacteriaceae. The PubMed and Scopus …

Acinetobacter: an old friend, but a new enemy

KJ Towner - Journal of Hospital Infection, 2009 - Elsevier
Acinetobacter emerged as a significant nosocomial pathogen during the late 1970s,
probably as a consequence, at least in part, of increasing use of broad-spectrum antibiotics …

Treatment of Acinetobacter Infections

J Fishbain, AY Peleg - Clinical infectious diseases, 2010 - academic.oup.com
Acinetobacter baumannii remains an important and difficult-to-treat pathogen whose
resistance patterns result in significant challenges for the clinician. Despite the prevalence …

Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy

AP Zavascki, CG Carvalhaes, RC Picao… - Expert review of anti …, 2010 - Taylor & Francis
Pseudomonas aeruginosa and Acinetobacter baumannii are major nosocomial pathogens
worldwide. Both are intrinsically resistant to many drugs and are able to become resistant to …

Current control and treatment of multidrug-resistant Acinetobacter baumannii infections

DE Karageorgopoulos, ME Falagas - The Lancet infectious diseases, 2008 - thelancet.com
Institutional outbreaks caused by Acinetobacter baumannii strains that have acquired
multiple mechanisms of antimicrobial drug resistance constitute a growing public-health …

Resistance to polymyxins: mechanisms, frequency and treatment options

ME Falagas, PI Rafailidis, DK Matthaiou - Drug resistance updates, 2010 - Elsevier
Polymyxins act by binding to lipid A moiety of the bacterial lipopolysaccharide and
subsequently disintegrating the bacterial membranes. The most important mechanism of …

Multidrug-resistant Gram-negative infections: what are the treatment options?

H Giamarellou, G Poulakou - Drugs, 2009 - Springer
The emergence of multidrug-resistant (MDR) Gram-negative bacilli creates a challenge in
the treatment of nosocomial infections. While the pharmaceutical pipeline is waning, two …

Efficacy and safety of tigecycline: a systematic review and meta-analysis

D Yahav, A Lador, M Paul… - Journal of antimicrobial …, 2011 - academic.oup.com
Background Tigecycline is a novel glycylcycline that exhibits broad-spectrum antibacterial
activity. Recently, the US FDA issued a warning concerning increased mortality with …