The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via
mechanical and electrical junctions. Although described in some detail by light microscopy …

This review presents an extensively integrated model of the cardiac intercalated disc (ID), a
highly orchestrated structure that connects adjacent cardiomyocytes. Classically, three main …

Gap junctions, composed of proteins from the connexin gene family, are highly dynamic
structures that are regulated by kinase-mediated signaling pathways and interactions with …

Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate
direct intercellular communication, a critical feature for the development, function, and …

Connexins are widely distributed proteins in the body that are crucially important for heart
and brain functions. Six connexin subunits form a connexon or hemichannel in the plasma …

Gap junctions are specialized membrane domains containing tens to thousands of
intercellular channels. These channels permit exchange of small molecules (< 1000 Da) …

Gap junctional channels are a class of membrane channels composed of transmembrane
channel-forming integral membrane proteins termed connexins, innexins or pannexins that …

That an alteration of the intestinal permeability is associated with gut barrier function has
been increasingly evident, which plays an important role in human and animal health …

It has become increasingly clear that the accumulation of proteins in specific regions of the
plasma membrane can facilitate cellular communication. These regions, termed signaling …

Popeye domain containing (Popdc) proteins are a unique family, which combine several
different properties and functions in a surprisingly complex fashion. They are expressed in …