A new class of biological ion-driven rotary molecular motors with 5: 2 symmetry

M Rieu, R Krutyholowa, NMI Taylor… - Frontiers in …, 2022 - frontiersin.org
Several new structures of three types of protein complexes, obtained by cryo-electron
microscopy (cryo-EM) and published between 2019 and 2021, identify a new family of …

Energization of outer membrane transport by the ExbB ExbD molecular motor

V Braun, AC Ratliff, H Celia… - Journal of Bacteriology, 2023 - Am Soc Microbiol
The outer membranes (OM) of Gram-negative bacteria contain a class of proteins (TBDTs)
that require energy for the import of nutrients and to serve as receptors for phages and …

Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility

ST Islam, NY Jolivet, C Cuzin, AM Belgrave, L My… - Science …, 2023 - science.org
The predatory deltaproteobacterium Myxococcus xanthus uses a helically-trafficked motor at
bacterial focal-adhesion (bFA) sites to power gliding motility. Using total internal reflection …

Tunable force transduction through the Escherichia coli cell envelope

DP Williams-Jones, MN Webby… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane (OM) of Gram-negative bacteria is not energised and so processes
requiring a driving force must connect to energy-transduction systems in the inner …

A molecular switch controls assembly of bacterial focal adhesions

B Attia, L My, JP Castaing, C Dinet, H Le Guenno… - Science …, 2024 - science.org
Cell motility universally relies on spatial regulation of focal adhesion complexes (FAs)
connecting the substrate to cellular motors. In bacterial FAs, the Adventurous gliding motility …

How Bacteria Establish and Maintain Outer Membrane Lipid Asymmetry

WB Tan, SS Chng - Annual Review of Microbiology, 2024 - annualreviews.org
Gram-negative bacteria build an asymmetric outer membrane (OM), with
lipopolysaccharides (LPS) and phospholipids (PLs) occupying the outer and inner leaflets …

The Tol-Pal system of Acinetobacter baumannii is important for cell morphology, antibiotic resistance and virulence

JJ Hubloher, L Van der Sande, C Schaudinn… - International …, 2023 - Springer
Acinetobacter baumannii is an opportunistic human pathogen that has become a global
threat to healthcare institutions. This Gram-negative bacterium is one of the most successful …

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins

K Nakanishi, K Kojima, Y Sowa… - The Journal of Physical …, 2024 - ACS Publications
Proton (H+) motive force (PMF) serves as the energy source for the flagellar motor rotation,
crucial for microbial motility. Here, to control PMF using light, we introduced light-driven …

A very versatile molecular machine

MD Manson - Journal of Bacteriology, 2024 - journals.asm.org
In this issue (J Bacteriol. 206: e0014024, https://doi. org/10.1128/jb. 00140-24), Ridone and
Baker describe hybrids between two 5: 2 heteroheptameric ion-powered motors. Chimeras …

Exploring Flexibility and Folding Patterns Throughout Time in Voltage Sensors

A García-Morales, D Balleza - Journal of Molecular Evolution, 2023 - Springer
The voltage-sensing domain (VSD) is a module capable of responding to changes in the
membrane potential through conformational changes and facilitating electromechanical …