R Bai, Z Lv, D Xu, J Cui - Biomarker research, 2020 - Springer
Although the clinical development of immune checkpoint inhibitors (ICIs) therapy has ushered in a new era of anti-tumor therapy, with sustained responses and significant …
LE Hendriks, KM Kerr, J Menis, TS Mok… - Annals of …, 2023 - annalsofoncology.org
Diagnosis of tumour type allows prognostication and triage for biomarker testing (see the Supplementary Material Section 3 and Supplementary Figure S1, available at https://doi …
G Raghu, KC Wilson - The Lancet Respiratory Medicine, 2020 - thelancet.com
COVID-19 is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first case was identified, 1 the rapid emergence of …
G Middleton, K Brock, J Savage, R Mant… - The Lancet …, 2020 - thelancet.com
Background Therapeutic blockade of the axis of programmed cell death 1 (PD-1) and its ligand (PD-L1) has transformed the management of non-small-cell lung cancer (NSCLC) …
R Ferrara, M Naigeon, E Auclin, B Duchemann… - Clinical Cancer …, 2021 - AACR
Abstract Purpose: CD28, CD57, and KLRG1 have been previously identified as markers of T- cell immunosenescence. The impact of immunosenescence on anti-PD (L)-1 (ICI) or …
NE Ready, C Audigier-Valette… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background CheckMate 817, a phase 3B study, evaluated flat-dose nivolumab plus weight- based ipilimumab in patients with metastatic non-small cell lung cancer (NSCLC). Here, in …
CJ Presley, F Gomes, CE Burd… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Cancer is a disease of older adults. The median age at cancer diagnosis is 66 years and median age at cancer-related death is 72 years. 1 Older adults represent one of the fastest …
Abstract Background Immune checkpoint inhibitors (ICIs) are standard of care in advanced non-small cell lung cancer (NSCLC), however their status in patients with poor performance …
K Morimoto, T Yamada, T Yokoi, T Kijima, Y Goto… - Lung Cancer, 2021 - Elsevier
Objectives Combination therapy of immune checkpoint inhibitors and chemotherapy is considered to be one of the standard treatment options for patients with advanced non-small …