Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …
MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long… - MBio, 2017 - Am Soc Microbiol
For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to …
TubercuList (http://tuberculist. epfl. ch/), the relational database that presents genome- derived information about H37Rv, the paradigm strain of Mycobacterium tuberculosis, has …
Campylobacter jejuni is currently the leading cause of bacterial gastroenteritis in humans. Comparison of multiple Campylobacter strains revealed a high genetic and phenotypic …
Identifying genomic elements required for viability is central to our understanding of the basic physiology of bacterial pathogens. Recently, the combination of high-density …
RNA sequencing provides a new perspective on the genome of Mycobacterium tuberculosis by revealing an extensive presence of non-coding RNA, including long 5'and 3'untranslated …
L Solans, J Gonzalo-Asensio, C Sala, A Benjak… - PLoS …, 2014 - journals.plos.org
The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 …
G Oliva, T Sahr, C Buchrieser - FEMS microbiology reviews, 2015 - academic.oup.com
Sequencing-based studies have illuminated increased transcriptional complexity within the genome structure of bacteria and have resulted in the identification of many small regulatory …
P Sobrero, C Valverde - Critical reviews in microbiology, 2012 - Taylor & Francis
Most of the sequenced bacterial genomes contain a gene encoding a protein known as Hfq that resembles the eukaryotic RNA-binding proteins of the LSm family. It was originally …