Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and
Efficacy | Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In …

Spatial and temporal control over chemical and biological processes plays a key role in life,
where the whole is often much more than the sum of its parts. Quite trivially, the molecules of …

Photocleavable protecting groups (PPGs) are extensively used in chemical and biological
sciences. In their application, advantage is taken of using light as an external, non-invasive …

In vivo optogenetics and photopharmacology are two techniques for controlling neuronal
activity that have immense potential in neuroscience research. Their applications in tether …

Addictive drugs cause persistent restructuring of several neuronal cell types in the limbic
regions of brain thought to be responsible for long-term behavioral plasticity driving …

Light-controllable tools provide powerful means to manipulate and interrogate brain function
with relatively low invasiveness and high spatiotemporal precision. Although optogenetic …

The vast computational power of the brain has traditionally been viewed as arising from the
complex connectivity of neural networks, in which an individual neuron acts as a simple …

Two‐photon excitation microscopy is an alternative to confocal microscopy that provides
advantages for three‐dimensional and deep tissue imaging. This unit will describe the basic …

The possibility offered by photocontrolling the activity of biomolecules in vivo while recording
physiological parameters is opening up new opportunities for the study of physiological …

The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …