Diagnostic potential and future directions of biomarkers in gingival crevicular fluid and saliva of periodontal diseases: Review of the current evidence

NA Ghallab - Archives of oral biology, 2018 - Elsevier
Objectives The holy grail of biomarker research in periodontology is to develop a high
impact diagnostics which have a significant impact on clinical decision-making, patient …

Salivary cytokines as biomarkers of periodontal diseases

KM Jaedicke, PM Preshaw, JJ Taylor - Periodontology 2000, 2016 - Wiley Online Library
Research into biomarkers of periodontitis is driven by mainly three targets: to identify 'at
risk'patients before periodontal tissue destruction occurs; to determine disease activity and …

Periodontal disease and visfatin level: A systematic review and meta-analysis

M Bayani, MT Heidari, A Almasi-Hashiani - Plos one, 2023 - journals.plos.org
Visfatin is considered an inflammatory biomarker in periodontal disease (PD). In this meta-
analysis, we aimed to evaluate the relationship between Visfatin biomarker level with PD. In …

Periodontitis is associated with the increased levels of visfatin: a meta-analysis

J Zhu, S Zhang, J Shi, N Ning, Y Wei, Y Zhang - BMC Oral Health, 2023 - Springer
Objective Periodontitis is a common inflammatory disease associated with systemic factors.
Visfatin is a pleiotropic adipokine that exerts metabolic and immune functions. Studies have …

[HTML][HTML] Possible interaction between visfatin, periodontal infection, and other systemic diseases: A brief review of literature

M Bayani, M Pourali, M Keivan - European journal of dentistry, 2017 - thieme-connect.com
Gingivitis and periodontitis are common bacterial infections caused by a variety of
microorganisms. Despite the microorganisms' roles as etiologic agents, inflammation …

The role of visfatin levels in gingival crevicular fluid as a potential biomarker in the relationship between obesity and periodontal disease

D Çetiner, A Uraz, S Öztoprak, G Akça - Journal of Applied Oral …, 2019 - SciELO Brasil
Objectives Visfatin is an adipokine that plays an important role in immune functions as a
growth factor, enzyme, and pro-inflammatory mediator. We aimed to determine the levels of …

Filifactor alocis and Tumor Necrosis Factor-Alpha Stimulate Synthesis of Visfatin by Human Macrophages

AVB Nogueira, M Nokhbehsaim, A Damanaki… - International journal of …, 2021 - mdpi.com
There is little known about the effect of the periodontopathogen Filifactor alocis on
macrophages as key cells of the innate immune defense in the periodontium. Therefore, the …

Non‐surgical periodontal therapy reduces saliva adipokine and matrix metalloproteinase levels in periodontitis

E Özcan, N Işıl Saygun, MA Serdar… - Journal of …, 2016 - Wiley Online Library
Background: Adipokines enhance the synthesis of proinflammatory cytokines and matrix
metalloproteinases (MMPs), which play a role in extracellular matrix degeneration. The aim …

Is periodontal inflamed surface area associated with serum and salivary levels of IL-1β, visfatin, and omentin-1 in overweight/obese patients?

ES Kemer Doğan, N Duran - Clinical Oral Investigations, 2022 - Springer
Objectives The aim of this study was to evaluate the levels of salivary and serum interleukin
(IL)-1β, visfatin, and omentin-1 in the relationship between periodontal disease and …

Expression of leptin and visfatin in gingival tissues of chronic periodontitis with and without type 2 diabetes mellitus: a study using enzyme‐linked immunosorbent …

NA Ghallab, EM Amr, OG Shaker - Journal of periodontology, 2015 - Wiley Online Library
Background: The aim of this study is to investigate the protein and gene expression of leptin
and visfatin in gingival tissue from patients with chronic periodontitis (CP), patients with CP …