Research on tumor immunotherapy has made tremendous progress in the past decades,
with numerous studies entering the clinical evaluation. The cancer vaccine is considered a …

Immune checkpoint inhibitors (ICI) used for cancer immunotherapy were shown to boost the
existing anti-tumor immune response by preventing the inhibition of T cells by tumor cells …

Tumor-associated myeloid cells (TAMCs) are among the most important immune cell
populations in the tumor microenvironment, and play a significant role on the efficacy of …

Dysregulated host immune responses to infection often occur, leading to sepsis, multiple
organ failure, and death. Some patients rapidly recover from sepsis, but many develop …

Immunotherapy is a promising approach to treating various types of cancers, including
hepatocellular carcinoma (HCC). While single immunotherapy drugs show limited …

Initially identified as a T lymphocyte-elicited inhibitor of macrophage motility, macrophage
migration inhibitory factor (MIF) has since been found to be expressed by nearly every …

Cold-inducible RNA-binding protein (CIRP) was discovered 2 decades ago while studying
the mechanism of cold stress adaptation in mammals. Since then, the role of intracellular …

Simple Summary The present article reviews the state of the art of metronomic
chemotherapy use to treat the principal types of cancers, namely breast, non-small cell lung …

Clinical and technological advances promoting early hemorrhage control and physiologic
resuscitation as well as early diagnosis and optimal treatment of sepsis have significantly …

Chronic immune activation and inflammation are unwanted consequences of many
pathological conditions, since they could lead to tissue damage and immune exhaustion …