Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Despite the recent advances in controlling some viral pathogens, most viral infections still
lack specific treatment. Indeed, the need for effective therapeutic strategies to combat 'old' …

Flaviviruses are known to cause a variety of diseases in humans in different parts of the
world. There are very limited numbers of antivirals to combat flavivirus infection, and …

Zika virus is an emerging flavivirus that causes the neurodevelopmental congenital Zika
syndrome and that has been linked to the neuroinflammatory Guillain–Barré syndrome. The …

In 1947, Zika virus (ZIKV), a mosquito-borne flavivirus was identified in Uganda and
subsequently spread to Asia and the Pacific regions. In 2015, it was introduced in Brazil …

Since the start of the pandemic, SARS-CoV-2 has already infected more than 250 million
people globally, with more than five million fatal cases and huge socio-economic losses. In …

Since the ZIKV outbreak in Brazil in 2015, the scientific community has joined efforts to
gather more information on the epidemiology, clinical features and pathogenicity of the virus …

In recent years, the Zika virus has emerged from a neglected flavivirus to a health-
threatening pathogen that causes epidemic outbreaks associated with neurological …

The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion …

Emerging viruses are a major threat to human health. Recent outbreaks have emphasized
the urgent need for new antiviral treatments. For several pathogenic viruses, considerable …