Significance: Cancer cells accumulate high levels of iron and reactive oxygen species
(ROS) to promote their high metabolic activity and proliferation rate. However, high levels of …

A novel family of 2Fe–2S proteins, the NEET family, was discovered during the last decade
in numerous organisms, including archea, bacteria, algae, plant and human; suggesting an …

Highlights•Properties and functions of biological Fe–S clusters with His-ligands are
examined.•Rieske clusters show increased redox potential and PCET due to His …

Intermittent voltage supply has been reported to improve the performance of electro-assisted
anaerobic digestion but has not been well understood. In this study, an intermittent voltage …

Human mitoNEET (mNT) is the first identified Fe-S protein of the mammalian outer
mitochondrial membrane. Recently, mNT has been implicated in cytosolic Fe-S repair of a …

NEET proteins comprise a new class of [2Fe-2S] cluster proteins. In human, three genes
encode for NEET proteins: cisd1 encodes mitoNEET (mNT), cisd2 encodes the Nutrient …

Despite the number of cellular and pathological mitoNEET-related processes, very few
details are known about the mechanism of action of the protein. The recently discovered …

Metal ions are commonly found as protein co-factors in biology, and it is estimated that over
a quarter of all proteins require a metal cofactor. The distribution and utilization of metals in …

The human mitochondrial outer membrane protein mitoNEET is a novel target of the type II
diabetes drug pioglitazone. The C-terminal cytosolic domain of mitoNEET hosts a redox …

Iron-sulfur proteins are ubiquitous in nature, acting as electron carriers and catalysts. Hence,
a plethora of synthetic analogs has been prepared to serve as active site models. However …