Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders

S Breit, A Kupferberg, G Rogler, G Hasler - Frontiers in psychiatry, 2018 - frontiersin.org
The vagus nerve represents the main component of the parasympathetic nervous system,
which oversees a vast array of crucial bodily functions, including control of mood, immune …

A network-based neurobiological model of PTSD: evidence from structural and functional neuroimaging studies

TJ Akiki, CL Averill, CG Abdallah - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review Although a fine-grained understanding of the neurobiology of
posttraumatic stress disorder (PTSD) is yet to be elucidated, the last two decades have seen …

The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

CG Abdallah, G Sanacora, RS Duman… - Pharmacology & …, 2018 - Elsevier
The discovery of the antidepressant effects of ketamine has opened a breakthrough
opportunity to develop a truly novel class of safe, effective, and rapid-acting antidepressants …

The neurobiology and pharmacotherapy of posttraumatic stress disorder

CG Abdallah, LA Averill, TJ Akiki, M Raza… - Annual review of …, 2019 - annualreviews.org
New approaches to the neurobiology of posttraumatic stress disorder (PTSD) are needed to
address the reported crisis in PTSD drug development. These new approaches may require …

Default mode network abnormalities in posttraumatic stress disorder: A novel network-restricted topology approach

TJ Akiki, CL Averill, KM Wrocklage, JC Scott, LA Averill… - Neuroimage, 2018 - Elsevier
Disruption in the default mode network (DMN) has been implicated in numerous
neuropsychiatric disorders, including posttraumatic stress disorder (PTSD). However …

[HTML][HTML] Dysregulation of inflammation, neurobiology, and cognitive function in PTSD: an integrative review

MM Quinones, AM Gallegos, FV Lin… - Cognitive, Affective, & …, 2020 - Springer
Compelling evidence from animal and human research suggest a strong link between
inflammation and posttraumatic stress disorder (PTSD). Furthermore, recent findings support …

Involvement of the brain–heart axis in the link between PTSD and cardiovascular disease

AV Seligowski, TK Webber, PJ Marvar… - Depression and …, 2022 - Wiley Online Library
Posttraumatic stress disorder (PTSD) has long been associated with a heightened risk of
cardiovascular disease (CVD). A number of mechanisms have been implicated to underlie …

Involvement of nuclear factor-κB in inflammation and neuronal plasticity associated with post-traumatic stress disorder

S Gupta, RS Guleria - Cells, 2022 - mdpi.com
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition which develops
either due to stress or witnessing a traumatic situation. PTSD is characterized by acute and …

Grey matter volume reductions of the left hippocampus and amygdala in PTSD: a coordinate-based meta-analysis of magnetic resonance imaging studies

A Del Casale, S Ferracuti, AS Barbetti… - …, 2022 - karger.com
Introduction: In recent years, research on posttraumatic stress disorder (PTSD) focused on
the description of different biological correlates of illness. Morphological changes of different …

The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths

OT Ousdal, AM Milde, GS Hafstad, E Hodneland… - Translational …, 2020 - nature.com
The amygdala is a core component in neurobiological models of stress and stress-related
pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have …