Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria
through an autophagy mechanism, thus maintaining mitochondria and intracellular …

Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

Background Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer.
Although most patients are initially sensitive to first-line combination chemotherapy with …

Globally, clear-cell renal cell carcinoma (ccRCC) represents the most prevalent type of
kidney cancer. Surgery plays a key role in the treatment of this cancer, although one third of …

Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Continuous proliferation of tumor cells requires constant adaptations of energy metabolism
to rapidly fuel cell growth and division. This energetic adaptation often comprises …

Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

Mitochondria in the cell are the center for energy production, essential biomolecule
synthesis, and cell fate determination. Moreover, the mitochondrial functional versatility …

Cellular ROS production participates in various cellular functions but its accumulation
decides the cell fate. Malignant cells have higher levels of ROS and active antioxidant …

The drug-tolerant persister (DTP) state enables cancer cells to evade cytotoxic stress from
anticancer therapy. However, the mechanisms governing DTP generation remain poorly …