Deciphering miRNAs' action through miRNA editing

M Correia de Sousa, M Gjorgjieva, D Dolicka… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene
expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) …

Regulation of microRNA function in animals

LFR Gebert, IJ MacRae - Nature reviews Molecular cell biology, 2019 - nature.com
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …

The non-canonical aspects of microRNAs: many roads to gene regulation

CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

Endogenous microRNA sponges: evidence and controversy

DW Thomson, ME Dinger - Nature Reviews Genetics, 2016 - nature.com
The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper

B Mateescu, EJK Kowal, BWM Van Balkom… - Journal of …, 2017 - Taylor & Francis
The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …

Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease

D Santovito, C Weber - Nature Reviews Cardiology, 2022 - nature.com
Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

Posttranslational control of HuR function

I Grammatikakis, K Abdelmohsen… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
The RNA‐binding protein HuR (human antigen R) associates with numerous transcripts,
coding and noncoding, and controls their splicing, localization, stability, and translation …

Extracellular miRNAs and cell–cell communication: problems and prospects

J Makarova, A Turchinovich, M Shkurnikov… - Trends in Biochemical …, 2021 - cell.com
miRNAs are short RNA molecules regulating multiple cellular processes through post-
transcriptional gene silencing. Over the past decade, miRNAs have been found in the …

[HTML][HTML] Circular RNAs: A novel type of non-coding RNA and their potential implications in antiviral immunity

M Wang, F Yu, W Wu, Y Zhang, W Chang… - … journal of biological …, 2017 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a novel type of non-coding RNAs (ncRNAs), are ubiquitously
expressed in eukaryotic cells during post-transcriptional processes. Unlike linear RNAs …

Reversible HuR‐micro RNA binding controls extracellular export of miR‐122 and augments stress response

K Mukherjee, B Ghoshal, S Ghosh, Y Chakrabarty… - EMBO …, 2016 - embopress.org
Abstract micro RNA s (mi RNA s), the tiny but stable regulatory RNA s in metazoan cells, can
undergo selective turnover in presence of specific internal and external cues to control …