Recent pre-clinical and clinical studies have shown that stem cell-based therapies hold
tremendous promise for the treatment of human disease. Mesenchymal stem cells (MSC) …

EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …

Mesenchymal stromal cells (MSCs) are inherently tumor homing and can be isolated,
expanded, and transduced, making them viable candidates for cell therapy. This tumor …

Acute myeloid leukemia (AML) cells exhibit a high level of spontaneous apoptosis when
cultured in vitro but have a prolonged survival time in vivo, indicating that tissue …

Macrophage migration inhibitory factor (MIF) promotes leukocyte recruitment to sites of
inflammation. However, whether this stems from a direct effect on leukocyte migration is …

Adult stem cells hold great promise for wound healing and tissue regeneration.
Mesenchymal stem cells (MSCs), for example, have been shown to play a role in tissue …

Mesenchymal stem cells (MSCs) are able to home and migrate into damaged tissues and
are thus, considered an optimal therapeutic strategy for clinical use. We previously …

Mesenchymal stem cells (MSCs) have emerged as a promising cellular vehicle for gene
therapy of malignant gliomas due to their property of tumor tropism. However, MSCs may …

Stem cells have inherent tumor‑trophic migratory properties and can serve as vehicles for
delivering effective, targeted therapy to isolated tumors and metastatic disease, making them …

As an important component of the immunosuppressive tumor microenvironment (TME), it
has been established that mesenchymal stem cells (MSCs) promote the progression of …