Genomic approach to selective vulnerability of the hippocampus in brain ischemia–hypoxia

R Schmidt-Kastner - Neuroscience, 2015 - Elsevier
Transient global ischemia selectively damages neurons in specific brain areas. A
reproducible pattern of selective vulnerability is observed in the dorsal hippocampus of …

Hippocampus—related cognitive and affective impairments in patients with breast cancer—A systematic review

X Peukert, K Steindorf, SB Schagen, A Runz… - Frontiers in …, 2020 - frontiersin.org
Background: Although improvements in medical treatment lead to a steadily rising survival
rate of breast cancer patients (BCP), it is associated with a decrease in cognitive and …

Methods for proteogenomics data analysis, challenges, and scalability bottlenecks: a survey

MU Tariq, M Haseeb, M Aledhari, R Razzak… - Ieee …, 2020 - ieeexplore.ieee.org
Big Data Proteogenomics lies at the intersection of high-throughput Mass Spectrometry (MS)
based proteomics and Next Generation Sequencing based genomics. The combined and …

[HTML][HTML] Sea cucumber peptides protect against memory impairment by regulating dopamine/serotonin metabolization and synapse plasticity of mice hippocampus

Z Lu, L Dong, D Chen, S Lin - Journal of Functional Foods, 2023 - Elsevier
With the increase of social stress and brain aging, memory impairment has become a
serious problem. Previous studies have shown preliminary neuroprotective evidence of sea …

CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer's disease

M Mendioroz, N Celarain, M Altuna… - Alzheimer's research & …, 2016 - Springer
Background CRTC1 (CREB regulated transcription coactivator 1) gene plays a role in
synaptic plasticity, learning and long-term memory formation in the hippocampus. Recently …

Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by 1H-NMR Dynamic Mapping Method

T Liu, Z Li, J He, N Yang, D Han, Y Li, X Tian, H Liu… - Neuroscience …, 2020 - Springer
Abnormal postoperative neurobehavioral performance (APNP) is a common phenomenon in
the early postoperative period. The disturbed homeostatic status of metabolites in the brain …

Gene Ontology: a resource for analysis and interpretation of Alzheimer's disease data

B Kramarz, RC Lovering - Exon Publications, 2019 - exonpublications.com
Gene Ontology (GO) is a universal resource for analyses and interpretation of high-
throughput biological datasets. GO is developed and curated by several different groups …

Testing of geroprotectors in experiments on cell cultures: pros and cons

AN Khokhlov, GV Morgunova - 2017 - books.rsc.org
According to the classic definition of aging we share, it is a combination of changes in an
organism leading to an increase in the probability of its death (rate of mortality). 1–4 It should …

Homogenous and microbeam X-ray radiation induces proteomic changes in the brains of irradiated rats and in the brains of nonirradiated cage mate rats

R Smith, J Wang, C Seymour… - Dose …, 2018 - journals.sagepub.com
To evaluate microbeam radiation therapy (MRT), for brain tumor treatment, the bystander
effect in nonirradiated companion animals was investigated. Adult rats were irradiated with …

Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues

G Budak, S Dash, R Srivastava, SA Lachke… - Experimental eye …, 2018 - Elsevier
Advances in sequencing have facilitated nucleotide-resolution genome-wide transcriptomic
profiles across multiple mouse eye tissues. However, these RNA sequencing (RNA-seq) …