The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …

Background Over the past 25 years, researchers have performed> 120 randomized
controlled trials (RCTs) illustrating short courses to be non-inferior to long courses of …

Importance The optimal dose and duration of oral amoxicillin for children with community-
acquired pneumonia (CAP) are unclear. Objective To determine whether lower-dose …

substantial group of patients who can safely be treated with 3 days of antibiotics. However,
of the 706 patients assessed for eligibility on day 3 of therapy, only 310 were eligible for …

Like all fields of medicine, Infectious Diseases is rife with dogma that underpins much
clinical practice. In this study, we discuss 2 specific examples of historical practice that have …

Community-acquired pneumonia is an important cause of morbidity and mortality. It can be
caused by bacteria, viruses, or fungi and can be prevented through vaccination with …

Antibiotic resistance is a major health problem and will be probably one of the leading
causes of deaths in the coming years. One of the most effective ways to fight against …

The traditional picture of cancer patients as weak individuals requiring maximum rest and
protection is beginning to dissolve. Too much focus on the medical side and one's own …

Background Studies comparing shorter and longer antibiotic treatment durations are
increasingly common. Randomized controlled trials (RCTs) are an ideal methodological …

Background Despite antibiotic stewardship programs existing in most acute care hospitals,
there continues to be variation in appropriate antibiotic use. While existing research …