PCL-PEG copolymer based injectable thermosensitive hydrogels

MR Dethe, A Prabakaran, H Ahmed, M Agrawal… - Journal of Controlled …, 2022 - Elsevier
A number of stimuli-responsive-based hydrogels has been widely explored in biomedical
applications in the last few decades because of their excellent biodegradability and …

Polylactic acid (PLA) controlled delivery carriers for biomedical applications

B Tyler, D Gullotti, A Mangraviti, T Utsuki… - Advanced drug delivery …, 2016 - Elsevier
Polylactic acid (PLA) and its copolymers have a long history of safety in humans and an
extensive range of applications. PLA is biocompatible, biodegradable by hydrolysis and …

Neural tissue engineering: strategies for repair and regeneration

CE Schmidt, JB Leach - Annual review of biomedical …, 2003 - annualreviews.org
▪ Abstract Nerve regeneration is a complex biological phenomenon. In the peripheral
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …

Hydrogels and cell based therapies in spinal cord injury regeneration

RC Assunção-Silva, ED Gomes, N Sousa… - Stem cells …, 2015 - Wiley Online Library
Spinal cord injury (SCI) is a central nervous system‐(CNS‐) related disorder for which there
is yet no successful treatment. Within the past several years, cell‐based therapies have …

Biomaterial design strategies for the treatment of spinal cord injuries

KS Straley, CWP Foo, SC Heilshorn - Journal of neurotrauma, 2010 - liebertpub.com
The highly debilitating nature of spinal cord injuries has provided much inspiration for the
design of novel biomaterials that can stimulate cellular regeneration and functional recovery …

Injectable hydrogels for central nervous system therapy

MM Pakulska, BG Ballios, MS Shoichet - Biomedical materials, 2012 - iopscience.iop.org
Diseases and injuries of the central nervous system (CNS) including those in the brain,
spinal cord and retina are devastating because the CNS has limited intrinsic regenerative …

Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury

S Stokols, MH Tuszynski - Biomaterials, 2006 - Elsevier
Although several approaches to stimulate axonal regeneration after spinal cord injury have
succeeded in stimulating robust growth of axons into a lesion site, the growth is generally …

[图书][B] Encyclopedia of biomaterials and biomedical engineering

G Wnek, G Bowlin - 2008 - books.google.com
Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

Multiple-channel scaffolds to promote spinal cord axon regeneration

MJ Moore, JA Friedman, EB Lewellyn, SM Mantila… - Biomaterials, 2006 - Elsevier
As molecular, cellular, and tissue-level treatments for spinal cord injury are discovered, it is
likely that combinations of such treatments will be necessary to elicit functional recovery in …