One of the major causes of defective sperm function is oxidative stress, which limits the
fertilizing potential of these cells as the result of collateral damage to proteins and lipids in …

Secreted phospholipases A 2 (sPLA 2 s) form a widespread group of structurally-related
enzymes that catalyse the hydrolysis of the sn-2 ester bond of glycerophospholipids to …

Phthalic acid esters (PAEs) are recognized endocrine disruptors. Detection of PAEs in
semen from idiopathic infertile males suggests possible direct mechanisms of sperm toxicity …

Abstract Phospholipase A2 (PLA2) is involved in eicosanoid release, and F2‐isoprostanes
(F2‐IsoPs), as free radical‐generated eicosanoids released by PLA2, are indicators of …

Phospholipase A 2 (PLA 2) activity has been shown to be involved in the sperm acrosome
reaction (AR), but the molecular identity of PLA 2 isoforms has remained elusive. Here, we …

Background Sperm hyperactive motility has previously been shown to influence litter size in
pigs, but little is known about the underlying biological mechanisms. The aim of this study …

8-Hydroxyguanine (8-oxoG) is the most common oxidative DNA lesion and unrepaired 8-
oxoG is associated with DNA fragmentation in sperm. However, the molecular effects of 8 …

The efficiency of artificial insemination (AI) is greatly influenced by the quality of semen.
Spermatozoa and seminal plasma are found in semen, which play a role in the reproductive …

Platelet-activating factor (PAF) is a well-known marker for embryo quality and viability. For
the first time, we describe an intracellular localisation of PAF in oocytes and embryos of …

In mammals, the role of sperm in the process of fertilization is complex, and several well-
defined steps must occur for the sperm to fertilize with the oocyte. Phospholipases (PLs) …