Background Positron emission tomography (PET) is a powerful, non-invasive preclinical and
clinical nuclear imaging technique used in disease diagnosis and therapy assessment …

Over the last 2 decades or so, hypervalent iodine compounds, such as diaryliodonium salts
and aryliodonium ylides, have emerged as useful precursors for labeling homoarenes and …

With the development of positron emission tomography (PET) technology, a variety of PET
imaging agents labeled with radionuclide 18 F have been developed and widely used in the …

This chapter summarizes the increasing role that hypervalent aryliodine compounds,
especially aryliodine (III) compounds, are serving as precursors for biomedical radiotracers …

Objective Given the requirements of high sensitivity and spatial resolution, the development
of new positron emission tomography (PET) agents is required for PET renography. The …

Background: Para-18F-fluorohippuric acid (18F-PFH) and ortho-124I-iodohippuric acid
(124IOIH) were recently identified as potential radiotracers suitable for conducting …

Renography is a standard clinical diagnostic test frequently used to evaluate renal function
in patients with suspected renal disorders. It is conducted by dynamic planar imaging using …

Abstract Ortho-[131 I] iodohippurate [131 I] OIH (marketed as Hippuran I 131), a gold
standard for radionuclide renography, and [123 I] OIH were in clinical use for decades. Here …

The introduction of halogenated functional groups by hypervalent iodine (III) reagents has
proven to be a popular synthetic method in modern organic chemistry. Such diverse and …

In this dissertation is presented work to fulfil the thesis requirements for the Doctor of
Philosophy degree at University of Oslo. The work has been carried out in the group of PET …