Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …

Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

The malignant neoplasm of the cervix, cervical cancer, has effects on the reproductive tract.
Although infection with oncogenic human papillomavirus is essential for cervical cancer …

This dissertation traces the historical trajectory of cancer immunotherapy, beginning with
early attempts at vaccination in ancient civilizations to the development of monoclonal …

Background and objectives: Colorectal cancer (CRC) is the second most common cause of
cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This …

Highlights•The identification of novel drug targets is a key step in drug innovation.•Essential
genes are vital for organism survival and are promising drug targets.•We describe in detail …

The head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers
in the world, but robust biomarkers and diagnostics are still not available. This study …

Colorectal cancer is the third deadliest and fourth most diagnosed cancer. It is
heterogeneously driven by varied mutations and mutagens, and thus, it is challenging for …

Colon adenocarcinoma (COAD) is one of the most common malignant tumors. Tumor
mutation burden (TMB) has become an independent biomarker for predicting the response …

Background Circular RNAs (circRNAs) are widely expressed in mammals and can regulate
the development and progression of human tumors. has_circ_0015758 (circ-CFH) is an …