Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

The discovery of leptin was intrinsically associated with its ability to regulate body weight.
However, the effects of leptin are more far-reaching and include profound glucose-lowering …

β-sitosterol (SIT), the most abundant bioactive component of vegetable oil and other plants,
is a highly potent antidiabetic drug. Our previous studies show that SIT controls …

Sarcopenia, obesity and their coexistence, obese sarcopenia (OBSP) as well as
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …

The combination of aging populations with the obesity pandemic results in an alarming rise
in non-communicable diseases. Here, we show that the enigmatic adenosine A2B receptor …

Obesity is increasing at unprecedented levels globally, and the overall impact of obesity on
the various organ systems of the body is only beginning to be fully appreciated. Because of …

Skeletal muscle plays important roles in normal biological activities and whole-body energy
homeostasis in humans. The growth and development of skeletal muscle also directly …

Diabetes is currently a growing concern of the age. Prevention and treatment of diabetes is a
global health priority. Adiponectin is an adipocyte derived protein hormone that enhances …

Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Research investigators have shown a growing interest in investigating alterations underlying
skeletal muscle wasting in patients with cancer. However, skeletal muscle dysfunctions …