Slices of CNS tissue prepared from young rodents can be maintained in culture for many
weeks to months. The basic requirements are simple: a stable substratum, culture medium …

The hypothalamo-neurohypophysial system (HNS) is the major peptidergic neurosecretory
system through which the brain controls peripheral physiology. The hormones vasopressin …

Mammals manifest circadian behaviour timed by an endogenous clock in the hypothalamic
suprachiasmatic nucleus (SCN). Considerable progress has been made in identifying the …

Intracellular free Ca 2+ regulates diverse cellular processes, including membrane potential,
neurotransmitter release, and gene expression. To examine the cellular mechanisms …

This study aims to analyse a circadian rhythm of insulin secretion from isolated rat
pancreatic islets in vitro and its potential modulation by melatonin, the concentrations of …

Analysis of the interplay between cell proliferation and death has been greatly advantaged
by the development of CNS slice preparations. In slices, interactions between neurons and …

The suprachiasmatic nucleus (SCN) receives glutamatergic afferents from the retina and
serotonergic afferents from the midbrain, and serotonin (5-HT) can modify the response of …

The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a
circadian pacemaker. This study used multimicroelectrode plates to measure extracellular …

Ever since the locus of the brain clock in the suprachiasmatic nucleus (SCN) was first
described, methods available have both enabled and encumbered our understanding of its …

The neuropeptides oxytocin and vasopressin and the neurons in the hypothalamus that
synthesize them have been a rich source for the exploration and understanding of both the …