Gametes are cells that have the unique ability to give rise to new individuals as well as
transmit (epi) genetic information across generations. Generation of functionally competent …

Background: Ovotesticular disorder/difference of sex development (DSD) refers to the co-
presence of testicular and ovarian tissue in one individual. Childhood management is …

ABSTRACT Fibroblast growth factor 9 (Fgf9) is a well‐known factor that regulates bone
development; however, its function in bone homeostasis is still unknown. Previously, we …

Abstract 46, XY gonadal dysgenesis (GD) is a Disorder/Difference of Sex Development
(DSD) that can present with phenotypes ranging from ambiguous genitalia to complete male …

Background Understanding the role of cytokines in tooth development is critical for
advancing dental tissue engineering. Fibroblast growth factor 9 (FGF9) is the only FGF …

Cleft palate, a common global congenital malformation, occurs due to disturbances in
palatal growth, elevation, contact, and fusion during palatogenesis. The Fibroblast growth …

Human multiple synostoses syndrome 3 is an autosomal dominant disorder caused by
pathogenic variants in FGF9. Only two variants have been described in FGF9 in humans so …

The fibroblast growth factor (FGF) family includes 22 proteins in humans. Based on their
mode of action, there are three families of FGFs: paracrine FGFs (FGF 1–10, 16, 17, 18, 20 …

The term chimera refers to an organism with cell lines from two or more distinct zygotes.
Human chimerism may occur naturally or artificially. Although rare, advancements in …

目的: 观察成纤维细胞生长因子9 (fibroblast growth factor 9, Fgf9) 基因敲除小鼠模型中下颌骨
发育的骨质变化, 探讨Fgf9 参与下颌骨发育中的软骨成骨和膜内成骨的过程. 方法: 建立Fgf9 …