The mechanisms and treatments for sarcopenia: could exosomes be a perspective research strategy in the future?

S Rong, L Wang, Z Peng, Y Liao, D Li… - Journal of cachexia …, 2020 - Wiley Online Library
The age‐related loss of muscle mass and muscle function known as sarcopenia is a primary
contributor to the problems faced by the old people. Sarcopenia has been a major public …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

From the bench to the bedside: branched amino acid and micronutrient strategies to improve mitochondrial dysfunction leading to sarcopenia

M Romani, MM Berger, P D'Amelio - Nutrients, 2022 - mdpi.com
With extended life expectancy, the older population is constantly increasing, and
consequently, so too is the prevalence of age-related disorders. Sarcopenia, the …

[HTML][HTML] Impact of β− hydroxy-β− methylbutyrate (HMB) on muscle loss and protein metabolism in critically ill patients: A RCT

MV Viana, F Becce, O Pantet, S Schmidt, G Bagnoud… - Clinical Nutrition, 2021 - Elsevier
Purpose Muscle wasting deteriorates life quality after critical illness and increases mortality.
Wasting starts upon admission to intensive care unit (ICU). We aimed to determine whether …

Targeting FABP4 in elderly mice rejuvenates liver metabolism and ameliorates aging-associated metabolic disorders

J Lv, Y Hu, L Li, Y He, J Wang, N Guo, Y Fang, Q Chen… - Metabolism, 2023 - Elsevier
Introduction Aging is characterized by progressive metabolic dyshomeostasis that increases
morbidity and mortality. Solutions for optimizing healthy aging are challenged by lacking …

From mitochondria to healthy aging: the role of branched-chain amino acids treatment: MATeR a randomized study

I Buondonno, F Sassi, G Carignano, F Dutto, C Ferreri… - Clinical Nutrition, 2020 - Elsevier
Rationale Malnutrition often affects elderly patients and significantly contributes to the
reduction in healthy life expectancy, causing high morbidity and mortality. In particular …

[HTML][HTML] ω-3 polyunsaturated fatty acid supplementation improves postabsorptive and prandial protein metabolism in patients with chronic obstructive pulmonary …

MPKJ Engelen, R Jonker, H Sulaiman, HL Fisk… - The American Journal of …, 2022 - Elsevier
Background Disturbances in protein metabolism and impaired muscle health have been
observed in chronic obstructive pulmonary disease (COPD). The ω-3 (n–3) PUFAs EPA and …

Intestinal function is impaired in patients with chronic obstructive pulmonary disease

SK Kirschner, NEP Deutz, R Jonker, SWMO Damink… - Clinical Nutrition, 2021 - Elsevier
Background & aims Gastrointestinal symptoms are prevalent extrapulmonary systemic
manifestations of Chronic Obstructive Pulmonary Disease (COPD), but have been rarely …

Comprehensive metabolic amino acid flux analysis in critically ill patients

NEP Deutz, P Singer, RA Wierzchowska-McNew… - Clinical Nutrition, 2021 - Elsevier
Amino acid (AA) metabolism is severely disturbed in critically ill ICU patients. To be able to
make a more scientifically based decision on the type of protein or AA nutrition to deliver in …

Is β-hydroxy β-methylbutyrate an effective anabolic agent to improve outcome in older diseased populations?

MPKJ Engelen, NEP Deutz - … in Clinical Nutrition & Metabolic Care, 2018 - journals.lww.com
The older diseased population might benefit from dietary HMB because of its established
positive properties as well as its long lasting (pharmacological) effect. In addition to …