Globally, breast cancer is the most common cancer type and is one of the most significant
causes of deaths in women. To date, multiple clinical interventions have been applied …

A founder variant is a genetic alteration, that is inherited from a common ancestor together
with a surrounding chromosomal segment, and is observed at a high frequency in a defined …

In developing countries, breast cancer is diagnosed at a much younger age. In this study we
investigate the dichotomies between older and young breast cancer patients in our region …

Objective To investigate the prevalence and spectrum of BRCA1 and BRCA2 mutations in
Chinese Hakka patients with breast and ovarian cancer. Methods A total of 1,664 breast or …

Breast cancer is the most common cancer among women worldwide, and its incidence rate
is still increasing, especially among younger women. Nationally, it constitutes one-fifth of all …

Simple Summary This study examined the efficacy and diagnostic yield of founder variant
testing as an initial screening method for individuals with a personal or family history of …

Purpose Breast cancer (BC) is the most common form of female cancer around the world.
BC is mostly sporadic, and rarely hereditary. These hereditary forms are mostly BRCA1-and …

Background This paper explores and discusses local challenges oncologists face for
diagnosing and managing breast cancer patients with BRCA gene mutations in Jordan …

Background: The interplay between breast cancer treatment and osteoporosis has important
consequences for anticancer therapy and patient bone health. Many breast cancer therapies …

Background High prevalence of early-onset breast cancer (EOBC) has been reported in
Middle Eastern populations. For example, in Oman more than 50% of patients with breast …