Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

The concept that disease rooted principally in chronic aberrant constitutive and reactive
activation of mast cells (MCs), without the gross MC neoplasia in mastocytosis, first emerged …

Major advances have been made in understanding the biochemistry of essential fatty acids
(FA) and their interactions with metabolic pathways leading to the production of longer and …

Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible
prostaglandin endoperoxide synthases by serving as a substrate for the enzymes' …

Hepatic stellate cells (HSCs) constitute the liver sinusoid with Kupffer cells and liver
sinusoidal endothelial cells. While the sinusoid functions as the gateway to liver …

Despite the utility of cyclooxygenase (COX) inhibition as an antiinflammatory strategy,
prostaglandin (PG) products of COX-1 and-2 provide important regulatory functions in some …

Prostaglandin (PG) JZ and related compounds continue to be of interest in areas including
pharmacology, oncology, molecular biology and immunology. Since a comprehensive …

During the last decade intensive work on the relationships between the liver and the
arachidonic acid cascade has greatly expanded our knowledge of this area of research. The …

The tissue-specific distribution of tissue-type and urokinase-type plasminogen activator (t-PA
and u-PA) and their inhibitor type 1 (PAI-1) was analyzed at mRNA level in five major rat …

Hepatic glycogenolysis and gluconeogenesis are essential processes for the prevention of
hypoglycemia during short-term starvation. As has been calculated from stable isotope …