[HTML][HTML] Pseudomonas aeruginosa biofilms and their partners in crime

M del Mar Cendra, E Torrents - Biotechnology advances, 2021 - Elsevier
Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact
with a broad range of microorganisms have a substantial clinical impact. This review focuses …

[HTML][HTML] A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases

S He, J Gui, K Xiong, M Chen, H Gao, Y Fu - Journal of nanobiotechnology, 2022 - Springer
Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …

Ivermectin: an award-winning drug with expected antiviral activity against COVID-19

FR Formiga, R Leblanc, J de Souza Rebouças… - Journal of controlled …, 2021 - Elsevier
Ivermectin is an FDA-approved broad-spectrum antiparasitic agent with demonstrated
antiviral activity against a number of DNA and RNA viruses, including severe acute …

Inhalable MOF‐derived nanoparticles for sonodynamic therapy of bacterial pneumonia

X Pan, N Wu, S Tian, J Guo, C Wang… - Advanced Functional …, 2022 - Wiley Online Library
Clinical therapy of multidrug resistant (MDR) bacteria‐induced deep‐tissue infections such
as pneumonia is highly challenging. Ultrasound (US)‐induced sonodynamic therapy (SDT) …

[HTML][HTML] Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections

AK Shakya, M Al-Sulaibi, RR Naik, H Nsairat, S Suboh… - Polymers, 2023 - mdpi.com
The rise in the resistance to antibiotics is due to their inappropriate use and the use of a
broad spectrum of antibiotics. This has also contributed to the development of multidrug …

Nanoparticle delivery systems with cell-specific targeting for pulmonary diseases

Z Deng, GT Kalin, D Shi… - American journal of …, 2021 - atsjournals.org
Respiratory disorders are among the most important medical problems threatening human
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …

[HTML][HTML] Polymyxin delivery systems: Recent advances and challenges

NV Dubashynskaya, YA Skorik - Pharmaceuticals, 2020 - mdpi.com
Polymyxins are vital antibiotics for the treatment of multiresistant Gram-negative ESKAPE
pathogen infections. However, their clinical value is limited by their high nephrotoxicity and …

[HTML][HTML] Preparation of hybrid alginate-chitosan aerogel as potential carriers for pulmonary drug delivery

M Alnaief, RM Obaidat, MM Alsmadi - Polymers, 2020 - mdpi.com
This study aims to prepare hybrid chitosan-alginate aerogel microparticles without using
additional ionic crosslinker as a possible pulmonary drug delivery system. The …

Drug combinations for inhalation: Current products and future development addressing disease control and patient compliance

H Banat, R Ambrus, I Csóka - International Journal of Pharmaceutics, 2023 - Elsevier
Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

[HTML][HTML] Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned

F Bianco, F Salomone, I Milesi, X Murgia, S Bonelli… - Respiratory …, 2021 - Springer
Delivery of medications to preterm neonates receiving non-invasive ventilation (NIV)
represents one of the most challenging scenarios for aerosol medicine. This challenge is …