Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

[HTML][HTML] A new Borrelia on the block: Borrelia miyamotoi–a human health risk?

S Cutler, M Vayssier-Taussat, A Estrada-Peña… - …, 2019 - eurosurveillance.org
Background Borrelia miyamotoi clusters phylogenetically among relapsing fever borreliae,
but is transmitted by hard ticks. Recent recognition as a human pathogen has intensified …

Complement evasion by Lyme disease spirochetes

JT Skare, BL Garcia - Trends in microbiology, 2020 - cell.com
The complement system is an ancient arm of the innate immune system that plays important
roles in pathogen recognition and elimination. Upon activation by microbes, complement …

[HTML][HTML] Conformational dynamics of complement protease C1r inhibitor proteins from Lyme disease–and relapsing fever–causing spirochetes

S Roy, CE Booth, AD Powell-Pierce, AM Schulz… - Journal of Biological …, 2023 - ASBMB
Borrelial pathogens are vector-borne etiological agents known to cause Lyme disease,
relapsing fever, and Borrelia miyamotoi disease. These spirochetes each encode several …

Borrelia burgdorferi and Borrelia miyamotoi in Atlantic Canadian wildlife

CB Zinck, VK Lloyd - PLoS One, 2022 - journals.plos.org
Borrelia burgdorferi and Borrelia miyamotoi are tick-vectored zoonotic pathogens
maintained in wildlife species. Tick populations are establishing in new areas globally in …

Borrelia miyamotoi: 43 Cases Diagnosed in France by Real-Time PCR in Patients With Persistent Polymorphic Signs and Symptoms

M Franck, R Ghozzi, J Pajaud… - Frontiers in …, 2020 - frontiersin.org
Background: Borrelia species are divided into three groups depending on the induced
disease and the tick vector. Borrelia miyamotoi is a relapsing fever Borrelia but can induce …

[HTML][HTML] New Epitopes for the Serodiagnosis of Human Borreliosis

MET Alcón-Chino, VLN Bonoldi, RMR Pereira… - Microorganisms, 2024 - mdpi.com
Lyme disease, a zoonotic infection caused by the bacterium Borrelia burgdorferi, is
transmitted to humans through the bites of infected ticks. Its diagnosis primarily relies on …

[HTML][HTML] Combining short-and long-read sequencing unveils geographically structured diversity in Borrelia miyamotoi

D Hoornstra, KV Kuleshov, V Fingerle, S Hepner… - Iscience, 2024 - cell.com
Borrelia miyamotoi is an emerging Ixodes tick-borne human pathogen in the Northern
hemisphere. The aim of the current study was to compare whole genome sequences of B …

Immune evasion strategies of relapsing fever spirochetes

F Röttgerding, P Kraiczy - Frontiers in immunology, 2020 - frontiersin.org
Relapsing fever (RF) is claimed a neglected arthropod-borne disease caused by a number
of diverse human pathogenic Borrelia (B.) species. These RF borreliae are separated into …

[HTML][HTML] Identification of immunoreactive linear epitopes of Borrelia miyamotoi

R Tokarz, T Tagliafierro, A Caciula, N Mishra… - Ticks and tick-borne …, 2020 - Elsevier
Borrelia miyamotoi is an emerging tick-borne spirochete transmitted by ixodid ticks. Current
serologic assays for B. miyamotoi are impacted by genetic similarities to other Borrelia and …