Monoclonal antibodies are a growing class of targeted cancer therapeutics, characterized by
exquisite specificity, long serum half-life, high affinity and immune effector functions. In this …

Cancer is the leading cause of death worldwide. Cancer immunotherapy involves
reinvigorating the patient's own immune system to fight against cancer. While novel …

Despite the clinical success of monoclonal and bispecific antibodies, there are still
limitations in the therapeutic effect of malignant tumours, such as low response rate …

In the realm of hematologic disorders, acute leukemia is approached as an emergent
disease given the multitude of complications and challenges that present both as a result of …

Cytokine storm (CS) refers to the spontaneous dysregulated and hyper-activated
inflammatory reaction occurring in various clinical conditions, ranging from microbial …

Objectives Despite their efficacy, some immunotherapies have been shown to induce
immune-related adverse events, including the potentially life-threatening cytokine release …

目的建立细胞因子释放综合征(CRS) 的体外评价方法, 对试验体系细胞密度,
阳性药种类及浓度进行探索. 方法分别用CD3 抗体(OKT3)(0.1~ 5 μg), OKT3 (0.1~ 1 μg)+ …

贝林妥欧单抗治疗复发难治急性淋巴细胞白血病13例疗效及不良反应分析- PMC Back to Top
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Аннотация Актуальность. Несмотря на достигнутые успехи в лечении B-клеточного
острого лимфобластного лейкоза (В-ОЛЛ), актуальными вопросами остаются …

Objective To establish an in vitro evaluation method of cytokine release syndrome (CRS),
and explore the cell density, positive drug types and concentrations of the test system …