Most of the anti-inflammatory drugs in clinical practice are becoming outdated owing to their potential side and adverse effects. These are found to be highly unsafe for long term use …
The current work aims to design and synthesis a new series of isatin derivatives and greatly enhances their cytotoxic activity. The derivatives 3-((bromophenyl) imino)-1-(morpholino …
s-Triazine possesses an auspicious status in the field of drug discovery and development owing to its presence in many naturally occurring compounds as well as commercially …
AA Abu‐Hashem - Journal of Heterocyclic Chemistry, 2021 - Wiley Online Library
oxo‐4‐phenylbutanehydrazide 3 was reacted with aryl or alkyl isothiocyanates to give the corresponding N‐substituted‐2‐(4‐oxo‐4‐phenylbutanoyl) hydrazine‐1‐carbothioamide 4a …
Abstract Starting from 3‐oxo‐N‐(3‐pyridyl) butanamide, as key intermediate, the title compounds were synthesized in good yields. Reaction of the pyridine‐carboxamide 1 with …
Background Thiazole ring is one of the most important heterocycle scaffolds in organic and medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …
This study aims to synthesize a new series of furochromone derivatives, evaluate their antimicrobial properties, and improve the permeability of potent compounds to inhibit …
This review describes the synthesis and chemical reactivity of tetrahydrothieno [3, 2-b] quinoline derivatives through many reagents such as; 1, 2-dihydropyridine-3-carbonitrile; 1 …
Abstract The pyrido [2, 3‐d] pyrimidine moieties are one of the most biologically widespread heterocyclic compounds as antimicrobial, antioxidant, antitubercular, antiviral and anti …