Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

Introduction Cognitive reserve (CR) is a crucial factor in explaining individual differences in
the risk of Alzheimer's disease (AD) and cognitive decline. CR refers to the brain's ability to …

Alzheimer's disease (AD) develops along a continuum that spans years prior to diagnosis.
Decreased muscle function and mitochondrial respiration occur years earlier in those that …

Background The number of people with dementia is soaring. Cognitive reserve has been
thought to be associated with dementia risk. It is not clear at which period in the life course …

Although there is a clear link between lifestyle and cognitive health, the dissonance between
observational and intervention studies results reveals gaps in the knowledge of how to …

Background: Air pollution in later life has been associated with dementia; however, limited
research has investigated the association between air pollution across the life course, either …

Both Alzheimer's disease and vascular dementia are the result of disease processes that
typically develop over several decades. Population studies have estimated that more than …

Dementia is a progressive, debilitating cognitive disorder recognized as one of the greatest
challenges to global health in the 21st century. In recent years, dementia has gained …

Currently, 55 million people globally are living with dementia, making it the seventh leading
cause of death worldwide and one of the costliest conditions to society. This number is said …

Both Alzheimer's disease and vascular dementia are the result of disease processes that
typically develop over several decades. Population studies have estimated that more than …