Advanced wearable biosensors for the detection of body fluids and exhaled breath by graphene

SU Singh, S Chatterjee, SA Lone, HH Ho, K Kaswan… - Microchimica Acta, 2022 - Springer
Given the huge economic burden caused by chronic and acute diseases on human beings,
it is an urgent requirement of a cost-effective diagnosis and monitoring process to treat and …

Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications

L Dayon, O Cominetti, M Affolter - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …

Tear-based vibrational spectroscopy applied to amyotrophic lateral sclerosis

D Ami, A Duse, P Mereghetti, F Cozza… - Analytical …, 2021 - ACS Publications
Biofluid analysis by optical spectroscopy techniques is attracting considerable interest due
to its potential to revolutionize diagnostics and precision medicine, particularly for …

Interaction network of extracellular vesicles building universal analysis via eye tears: iNEBULA

L Hu, X Liu, Q Zheng, W Chen, H Xu, H Li, J Luo… - Science …, 2023 - science.org
Discovering the secrets of diseases from tear extracellular vesicles (EVs) is well-recognized
and appreciated. However, a precise understanding of the interaction network between EV …

[HTML][HTML] Diagnosis and biomarkers for ocular tuberculosis: From the present into the future

Z Ludi, AA Sule, RP Samy, I Putera, B Schrijver… - Theranostics, 2023 - ncbi.nlm.nih.gov
Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …

Using tears as a non-invasive source for early detection of breast cancer

A Daily, P Ravishankar, S Harms, VS Klimberg - PLoS One, 2022 - journals.plos.org
The changing expression levels of ocular proteins in response to systemic disease has been
well established in literature. In this study, we examined the ocular proteome to identify …

Single-tear proteomics: A feasible approach to precision medicine

E Ponzini, D Ami, A Duse, C Santambrogio… - International Journal of …, 2021 - mdpi.com
Lacrimal fluid is an attractive source of noninvasive biomarkers, the main limitation being the
small sample amounts typically collected. Advanced analytical methods to allow for …

Viscoelastic properties of the human tear film

A Recchioni, E Mocciardini, E Ponzini… - Experimental Eye …, 2022 - Elsevier
When considering eye blinking from a tribological perspective, tear viscosity is expected to
play a fundamental role. The application of rheological techniques to describe the tear film …

Comparison of different mass spectrometry workflows for the proteomic analysis of tear fluid

G Jones, TJ Lee, J Glass, G Rountree, L Ulrich… - International journal of …, 2022 - mdpi.com
The tear film is a multi-layer fluid that covers the corneal and conjunctival epithelia of the eye
and provides lubrication, nutrients, and protection from the outside environment. Tear fluid …

Mass Spectrometry–Based Proteogenomics: New Therapeutic Opportunities for Precision Medicine

SK Joshi, P Piehowski, T Liu… - Annual review of …, 2024 - annualreviews.org
Proteogenomics refers to the integration of comprehensive genomic, transcriptomic, and
proteomic measurements from the same samples with the goal of fully understanding the …