[HTML][HTML] Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
Entry of Listeria monocytogenes in mammalian epithelial cells: an updated view
J Pizarro-Cerdá, A Kühbacher… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Listeria monocytogenes is a bacterial pathogen that promotes its internalization into host
epithelial cells. Interaction between the bacterial surface molecules InlA and InlB and their …
epithelial cells. Interaction between the bacterial surface molecules InlA and InlB and their …
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Abstract Development of a highly effective vaccine or antibodies for the prevention and
ultimately elimination of malaria is urgently needed. Here we report the isolation of a number …
ultimately elimination of malaria is urgently needed. Here we report the isolation of a number …
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein
Immunization with attenuated Plasmodium falciparum sporozoites (PfSPZs) has been shown
to be protective against malaria, but the features of the antibody response induced by this …
to be protective against malaria, but the features of the antibody response induced by this …
Malaria parasite development in the mosquito and infection of the mammalian host
ASI Aly, AM Vaughan, SHI Kappe - Annual review of …, 2009 - annualreviews.org
Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host
A Coppi, R Natarajan, G Pradel, BL Bennett… - Journal of Experimental …, 2011 - rupress.org
Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the
mammalian liver. The sporozoite's major surface protein, circumsporozoite protein (CSP), is …
mammalian liver. The sporozoite's major surface protein, circumsporozoite protein (CSP), is …
[HTML][HTML] Looking under the skin: the first steps in malarial infection and immunity
Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes
Clinical malaria is associated with the proliferation of Plasmodium parasites in human
erythrocytes. The coordinated processes of parasite egress from and invasion into …
erythrocytes. The coordinated processes of parasite egress from and invasion into …
[HTML][HTML] Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass …
Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly
motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to …
motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to …
Malaria parasite liver infection and exoerythrocytic biology
AM Vaughan, SHI Kappe - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
In their infection cycle, malaria parasites undergo replication and population expansions
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …