Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities

PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …

Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

[HTML][HTML] Consensus nomenclature for reporting neovascular age-related macular degeneration data: consensus on neovascular age-related macular degeneration …

RF Spaide, GJ Jaffe, D Sarraf, KB Freund, SR Sadda… - Ophthalmology, 2020 - Elsevier
Purpose To establish a process to evaluate and standardize a state-of-the-art nomenclature
for reporting neovascular age-related macular degeneration (AMD) data. Design Consensus …

Angiopoietin/Tie2 signalling and its role in retinal and choroidal vascular diseases: a review of preclinical data

AM Joussen, F Ricci, LP Paris, C Korn… - Eye, 2021 - nature.com
The ang opoietin/t yrosine kinase with i mmunoglobulin and e pidermal growth factor
homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development …

Towards a better understanding of non-exudative choroidal and macular neovascularization

R Sacconi, S Fragiotta, D Sarraf, SVR Sadda… - Progress in Retinal and …, 2023 - Elsevier
Non-exudative macular and choroidal neovascularization (MNV and CNV) usually refers to
the entity of treatment-naïve type 1 neovascularization in the absence of associated signs of …

Age-related macular degeneration: pathophysiology, management, and future perspectives

R Flores, Â Carneiro, M Vieira, S Tenreiro… - Ophthalmologica, 2021 - karger.com
Among older adults, age-related macular degeneration (AMD) is a prevalent disabling
condition that begins as subtle visual disturbances and can progress to permanent loss of …

Optical coherence tomography angiography of asymptomatic neovascularization in intermediate age-related macular degeneration

L Roisman, Q Zhang, RK Wang, G Gregori, A Zhang… - Ophthalmology, 2016 - Elsevier
Purpose To determine whether angiography with swept-source (SS) optical coherence
tomography (OCT) identifies subclinical type 1 neovascularization in asymptomatic eyes …

Natural history of subclinical neovascularization in nonexudative age-related macular degeneration using swept-source OCT angiography

JR de Oliveira Dias, Q Zhang, JMB Garcia, F Zheng… - Ophthalmology, 2018 - Elsevier
Purpose Swept-source (SS) OCT angiography (OCTA) was used to determine the
prevalence, incidence, and natural history of subclinical macular neovascularization (MNV) …

Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography

TT Hormel, Y Jia, Y Jian, TS Hwang, ST Bailey… - Progress in Retinal and …, 2021 - Elsevier
Optical coherence tomographic angiography (OCTA) is a novel technology capable of
imaging retinal vasculature three-dimensionally at capillary scale without the need to inject …

Optical coherence tomography angiography of shallow irregular pigment epithelial detachments in pachychoroid spectrum disease

KK Dansingani, C Balaratnasingam, MA Klufas… - American journal of …, 2015 - Elsevier
Purpose To determine the proportion of shallow irregular pigment epithelial detachments in
eyes with pachychoroid features that harbor neovascular tissue and to study the morphology …