Aims Gut microbiota-derived metabolite trimethylamine-N-oxide (TMAO) is emerging as a
new potentially important cause of increased cardiovascular risk. The purpose of this meta …

Background Frailty is a geriatric syndrome that diminishes the potential for functional
recovery after a transcatheter aortic valve replacement (TAVR) or surgical aortic valve …

Importance The outcomes of patients with left ventricular (LV) dysfunction and secondary
mitral regurgitation (SMR) are still controversial. Objective To clarify the role of SMR in the …

Obesity has been associated with increased incidence of comorbidities and shorter life
expectancy, and it has generally been assumed that patients with obesity should have …

Background Malnutrition is a hallmark of frailty, is common among elderly patients, and is a
predictor of poor outcomes in patients with severe symptomatic aortic stenosis (AS). The …

Background Objective nutritional indexes have been shown to predict prognoses in some
clinical settings. We aimed to investigate the prognostic values of these indexes in patients …

Increased body mass index (BMI) is an established cardiovascular risk factor. The impact of
high BMI on vascular and bleeding complications in patients undergoing transcatheter aortic …

Leaflet thrombosis (LT) has been claimed as a potential cause of hemodynamic dysfunction
or bioprosthetic valve degeneration of transcatheter heart valves. Sparse and contrasting …

Objectives To determine whether long‐term behavioral intervention targeting weight loss
through increased physical activity and reduced caloric intake would alter cerebral blood …

Background: A paradoxical association of obesity with lower risk of transcatheter aortic valve
replacement (TAVR) outcomes has been reported. We aimed to systematically review the …